Aristolochicacidsodiumsalt 马兜铃酸钠盐

CAS 10190-99-5 MFCD00210760

化学结构图

10190-99-5
SMILES: [Na+].COC1=CC=CC2C3=C(C(=CC4OCOC=43)C([O-])=O)C(=CC=21)[N+]([O-])=O

化学属性

Mol. FormulaC17H10NNaO7
Mol. Weight363.25

别名和识别编码

Chemical NameAristolochicacidsodiumsalt
Synonym Aristolochic acid sodium salt
CAS Number10190-99-5
PubChem Substance ID24891454
EC Number233-463-4
MDL NumberMFCD00210760
Chemical Name Translation马兜铃酸钠盐
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分类

  • AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism
  • {SNA} Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism

相关文献及参考

  • 1. Levova, K., et al., Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model Toxicol. Sci. 121 , 43-56, (2011)
  • Kim, S.H., et al., Drosophila TRPA1 Channel Mediates Chemical Avoidance In Gustatory Receptor Neurons. Proc. Natl. Acad. Sci. U. S. A. 107 , 8440-5, (2010) 摘要

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T
Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSSF8281000
Precautionary statements
  • P301+P310
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Signal word Danger
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Lipids in Cell Signaling - Cell Signaling and Neuroscience
  5. Phospholipid Metabolism - Lipids in Cell Signaling
  6. Phospholipase Inhibitors - Phospholipid Metabolism
  1. Functional Group 官能团索引
  2. carboxylic acid salt

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