Propiophenone, 4'-methoxy-3-piperidino-, hydrochloride

CAS 1026-88-6 MFCD01576240

化学结构图

1026-88-6
SMILES: COc1ccc(C(=O)CCN2CCCCC2)cc1.Cl

化学属性

Mol. Weight283.83
Mol. FormulaC15H21NO2.ClH

别名和识别编码

Wiswesser Line NotationT6NTJ A2VR DO1 &GH
Chemical NamePropiophenone, 4'-methoxy-3-piperidino-, hydrochloride
Synonym 4-Methoxy-beta-(1-piperidyl)propiophenone hydrochloride Propiophenone, 4'-methoxy-beta-(1-piperidino)-, hydrochloride
CAS Number1026-88-6
InChIKeyCCGBIMUGLRDVOC-UHFFFAOYSA-N
PubChem Substance ID70563
InChIInChI=1S/C15H21NO2.ClH/c1-18-14-7-5-13(6-8-14)15(17)9-12-16-10-3-2-4-11-16;/h5-8H,2-4,9-12H2,1H3;1H
LabNetwork Molecule IDLN00452477
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安全信息

RTECSUH4375000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 137 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,994,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,559,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Behavioral - irritability
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 115,419,1955

系列性分类


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