Allyl bromide 3-溴丙烯(烯丙基溴)

CAS 106-95-6 MFCD00000244

化学结构图

106-95-6
SMILES: C=CCBr

化学属性

Mol. FormulaC3H5Br
Mol. Weight120.98
Refractive index1.4650 to 1.4710
Boiling Point
Density1.398
Melting PointNo Data Available
Flash Point-2.22°C
TSCAYes
Autoignition Point554 °F
Vapor Density4.2 (vs air)
Solubility不溶于水,溶于乙醇、乙醚、氯仿、四氯化碳、二硫化碳等多数有机溶剂。
Stability对热、光线和空气敏感
Danger-Level-
pH-:-
Redox-

别名和识别编码

Chemical NameAllyl bromide
Synonym 3-Bromo-1-propene 3-Brompropen 3-bromo-1-propen 3-bromo-1-propene 3-bromo-propen 3-溴-1-丙烯 3-溴-1-丙烯,烯丙基溴 3-溴丙烯 3-溴代丙烯 3-溴烯丙烯 Allyl Bromide (Stabilized with Propylene Oxide) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number106-95-6
PubChem Substance ID7841
EC Number203-446-6
Beilstein Registry Number605308
MDL NumberMFCD00000244
Reaxys-RN605308
Merck Number288
Chemical Name Translation3-溴丙烯(烯丙基溴)
Wiswesser Line NotationE2U1
LabNetwork Molecule IDLN00196351
InChIInChI=1S/C3H5Br/c1-2-3-4/h2H,1,3H2
Canonical SMILESC=CCBr
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分类

  • Chemical Synthesis, Others, Protecting and Derivatizing Reagents, Protection and Derivatization, Synthetic Reagents
  • {SNA} Chemical Synthesis, Other Protecting and Derivatizing Reagents, Protecting and Derivatizing Reagents, Protection and Derivatization, Synthetic Reagents
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Chemical Synthesis, Others, Protecting and Derivatizing Reagents,

产品应用

  • 本品用于有机合成,可用合成染料、香料;医药工业用于制“西可巴比妥”药物;农业用作土壤熏蒸剂。

相关文献及参考

  • Merck:14,288
  • Merck:14,288 Beilstein:1,201
  • Short: II/14a
  • Short: II/24B

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 3 F,T,N
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H300 Fatal if swallowed 吞食致命
  • H301 Toxic if swallowed 吞食有毒
  • H310 Fatal in contact with skin 皮肤接触致命
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H330 Fatal if inhaled 吸入致命
  • H331 Toxic if inhaled 吸入中毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H340 May cause genetic defects 可能导致遗传性缺陷
  • H350 May cause cancer 可能致癌
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUC7090000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P241+P242+P243
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P330+P331
  • P301+P330+P331+P310
  • P302+P350
  • P302+P352
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P337+P313
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R11 Highly flammable 非常易燃
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R45 May cause cancer 可能致癌
  • R46 May cause inheritable genetic damage 可能引起遗传基因损害
  • R50 Very toxic to aquatic organisms 对水生生物极毒
UN Number 1099 UN1099
Storage condition +4°C 2-8°C 4 4℃ Light Sensitive {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Packing GroupI
Hazard Class3/6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 4110 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 18(4),55,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 9,235,1989

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/m3/30M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAVUAI Fiziologicheski Aktivnye Veshchestva.  Physiologically Active
   Substances.  (Izdatel'stvo Naukova Dumka, Kiev, USSR)  No.1-    1966-
   Volume(issue)/page/year: 7,35,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   20,263,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   29,993,1980

Restrict -

其他信息

  • 用途一:用作医药中间体
  • 图谱信息:3-溴丙烯(106-95-6)核磁图( 13 CNMR) 3-溴丙烯(106-95-6)质谱(MS) 3-溴丙烯(106-95-6)核磁图( 1 HNMR) 3-溴丙烯(106-95-6)红外图谱(IR1)
  • 下游产品:佛手苷内酯 --> 丁香酚 --> 茴香脑 --> 1-辛烯 --> 异硫氰酸烯丙酯 --> 花椒毒醇 --> 3-羟基-3-甲基谷氨酸 --> 尼多克罗 --> 氯哌噻吨 --> 烯丙苯 --> 氟咯草酮 --> 2-甲氧基-3-溴丙烯 --> 罗库溴铵 --> 4-烯丙基苯甲醚 --> 烯丙基腈 --> 烯丙基三甲基硅烷
  • Acros Organics:烯丙基溴 Allylbromide,stabilized,99%(106-95-6)
  • 储运特性:库房通风低温干燥; 与氧化剂分开存放
  • 灭火剂:干粉、干砂、二氧化碳、泡沫、1211灭火剂
  • 爆炸物危险特性:与空气混合可爆
  • 可燃性危险特性:遇明火、高温、氧化剂易燃; 高热分解有毒溴化物气体
  • 有不愉快刺激气味。能与乙醇、氯仿、乙醚、二硫化碳和四氯化碳混溶,微溶于水。半数致死量(小鼠,腹腔)108mg/kg。有催泪性和腐蚀性。商品一般加有银绒作稳定剂。
  • MSDS 信息:烯丙基溴(106-95-6).msds
  • 用途三:本品用于有机合成,可用合成染料、香料;医药工业用于制“西可巴比妥”药物;农业用作土壤熏蒸剂。
  • F:8-19
  • 急性毒性:口服- 大鼠 LD50: 120 毫克/ 公斤; 腹腔- 小鼠 LD50: 48 毫克/ 公斤
  • 类别:易燃液体
  • 蒸气密度:4.2 (vs air)
  • 3-溴丙烯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80002126 烯丙基溴;溴丙烯;3-溴-1-丙烯 100ml 186元 2011/04/16 B0643 烯丙基溴 Allyl Bromide 25G 160元 2011/04/16 B0643 烯丙基溴 Allyl Bromide 500G 660元
  • 方法一:1.由烯丙醇溴化而得:向反应罐投入氢溴酸,在搅拌下加入硫酸、烯丙醇。升温回流2h,加热至8℃时有馏液蒸出,收集68-73℃馏分。水洗后,用无水硫酸钠脱水,过滤,得烯丙基溴。2.丙烯溴化法。
  • 外观性质:无色到淡黄色液体,有令人不愉快的刺激性气味。
  • 用途二:用于有机合成如合成染料、香料;医药工业上用于西可巴比妥的制造;农业上用作土壤熏蒸剂。
  • Sigma Aldrich:106-95-6(sigmaaldrich)
  • Alfa Aesar:3-溴-1-丙烯,烯丙基溴,99% Allyl bromide, 99%(106-95-6)
  • 毒性分级:高毒
  • 上游原料:丙烯醇
  • 海关编码:29033036
  • TCI Shanghai:烯丙基溴 Allyl Bromide,>;98.0%(GC)(106-95-6)
  • MOL 文件:106-95-6.mol

系列性分类