MAGAININ 1

CAS 108433-99-4 MFCD00133521

化学结构图

108433-99-4
SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O

化学属性

Mol. FormulaC112H177N29O28S
Mol. Weight2409.85

别名和识别编码

Chemical NameMagainin I
MDL NumberMFCD00133521
CAS Number108433-99-4
Synonym
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Antibacterial, Antibiotic Peptides,
  • {SNA} Antibacterial, Antibiotic Peptides, Antibiotics A to Z, Antibiotics G-M, Antifungal, Antiviral, Chemical Structure Class, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators, Immunomodulators and Antibiotics, Interferes with Cell Membrane Permeability (Ionophores), L - Z, Mechanism of Action, Peptides, Peptides and Proteins, Peptides for Cell Biology, Spectrum of Activity, 抗生素, 生化试剂, 细胞信号转导和神经科学, 细胞生物学
  • Antibacterial, Antibiotic Peptides, Antibiotic

相关文献及参考

  • Zasloff, M. Proc. Natl. Acad. Sci. U. S. A. 84 , 5449, (1987) 摘要
  • Giovannini, M.G., et al. Biochem. J. 243 , 113, (1987) 摘要
  • Vorland, L.H., et al., Initial binding sites of antimicrobial peptides in Staphylococcus aureus and Escherichia coli. Scand. J. Infect. Dis. 31 , 467-473, (1999) 摘要
  • Huang, H., Action of antimicrobial peptides: Two-state model. Biochemistry 39 , 8347, (2000) 摘要
  • Wieprecht, T., Binding of antibacterial magainin peptides to electrically neutral membranes: thermodynamics and structure. Biochemistry 38 , 10377, (1999) 摘要
  • Helmerhorst, E.J., A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides. FEBS Lett. 449 , 105, (1999) 摘要
  • Matsuzaki K., Magainins as paradigm for the mode of action of pore forming polypeptides. Biochim. Biophys. Acta 1376 , 391-400, (1998) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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