CAS 111469-81-9 MFCD00069313
化学结构图
SMILES: Cl.O[C@]12CC3=C(NC4C=CC=CC=43)[C@@H]3OC4C5=C(C[C@H]1N(CC1CC1)CC[C@]253)C=CC=4O
化学属性
| Mol. Formula | C26H26N2O3· HCl |
|---|---|
| Mol. Weight | 450.96 |
别名和识别编码
| Chemical Name | |
|---|---|
| Synonym | Naltrindole hydrochloride |
| MDL Number | MFCD00069313 |
| PubChem Substance ID | 24278062 |
| Chemical Name Translation |
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分类
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids - Opiod Antagonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, N, Neurobiology, Neuroscience, Opioid Antagonists, Opioids, Pharmacologicals, Proteins and Derivatives
相关文献及参考
- [2]. Mundra JJ, et al. Naltrindole inhibits human multiple myeloma cell proliferation in vitro and in a murine xenograft model in vivo. J Pharmacol Exp Ther. 2012 Aug;342(2):273-87.
- [3]. Chen YL, et al. Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells.
- [4]. Portoghese PS, et al. Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist. Eur J Pharmacol. 1988 Jan 27;146(1):185-6.
- [5]. Fernández B, et al. Postnatal naltrindole treatments induce behavioural modifications in preweanling rats. Neurosci Lett. 2000 Mar 31;283(1):73-6.
- [1]. Raynor K, et al. Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol. 1994 Feb;45(2):330-4.
- [1]. Raynor K, et al. Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol. 1994 Feb;45(2):330-4.
- [2]. Mundra JJ, et al. Naltrindole i
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