8-Hydroxyquinoline N-Oxide 8-羟基喹啉-N-氧化物

CAS 1127-45-3 MFCD00006739

化学结构图

1127-45-3
SMILES: [O-][n+]1cccc2cccc(O)c21

化学属性

Mol. FormulaC9 H7 N O2
Mol. Weight161.16
Melting Point135-138
Density1.422
Boiling Point145°C/15mmHg(lit.)

别名和识别编码

Chemical Name8-Hydroxyquinoline N-Oxide
CAS Number1127-45-3
Alfabeta NameHYDROXYQUINOLINEOXIDE 81--
MDL NumberMFCD00006739
Synonym 8-Hydroxyquinoline N-Oxide {} {} {} {} {} {} {ALD} 8-羟基喹啉氮氧化物; {} {} {} {} {} {} {} {SNA} 8-羟基喹啉氮氧化物 {} {} {} {} {} {} {} {} {SNA} 8-羟基喹啉-N-氧化物 {} {} {} {} {} {} {} {} {} {JNK} 8-Quinolinol N-oxide {} {} {} {} {} {} {} {} {} {} {hazard_com} 8-Hydroxyquinoline-N-oxide {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} 8-Hydroxyquinoline N-oxide
PubChem Substance ID14312
Beilstein Registry Number128737
EC Number214-430-3
Reaxys-RN128737
Chemical Name Translation8-羟基喹啉-N-氧化物
Wiswesser Line NotationT66 BNJ BO JQ
LabNetwork Molecule IDLN00175722
InChIInChI=1S/C9H7NO2/c11-8-5-1-3-7-4-2-6-10(12)9(7)8/h1-6,11H
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分类

  • Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines
  • {SA} Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines
  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; alcohol; 1fragment
  • {SNA} Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines

产品应用

  • A quinoline derivative; shows mutagenic activity.

相关文献及参考

  • Bradford, M., et al.: Anal. Biochem., 72, 248 (1976),
  • Beil. 21 ,V,3,276
  • Aldrich MSDS 1 , 1079:C / Corp MSDS 1 (1), 1961:C / FT-IR 2 (3), 3999:D / FT-IR 1 (2), 918:C / IR-Spectra (3), 1424:A / IR-Spectra (2), 1240:F / NMR-Reference 2 (2), 779:B / RegBook 1 (2), 2683:G
  • Short: III/10a Title: Structure Data of Organic Crystals: C ... C 15 Author: Schudt-Weitz, G.; Strell, I. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/10a Year: 1985 ISBN: 3-540-07834-7 ISBN: 978-3-540-07834-0 Internet Resource: DOI:10.1007/b19984 RefComment: XXII, 634 pages. Hardcover Abstract: The volume includes an alphabetical index of all substances and a separate "ring index" with all cyclic compounds.
  • Short: III/35E Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Oxygen-17 Author: Duddeck, H.; Toth, G.; Simon, A. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35E Year: 2002 Keyword: Alipathic and Aromatic hydrocarbons; Coupling constant j; Nuclear Magnetic Resonance; chemical shifts δ ISBN: 3-540-42501-2 ISBN: 978-3-540-42501-4 Internet Resource: DOI:10.1007/b92953 RefComment: VII, 230 pages. With CD-ROM., Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1 (subvol. C), carbon-13 (subvol. D), and oxygen-17 (subvol. E) compounds are tabulated together with the gross- and structure formulas and the most readily available solvents. Due to the large amount of the data merely chemical shifts are presented in the printed versions, and all the data, chemical shifts and coupling constants are provided on CD-ROM's.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commerci

安全信息

Warnings IRRITANT
WGK Germany3
RTECSVC8238500
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P317
  • P337+P317
  • P362+P364
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition +4°C 储存温度2-8℃ 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   60,405,1978

Hazard Class9
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
UN Number 3077
Packing GroupIII

其他信息

  • 8 - 羟基喹啉-N-氧化物是一种有毒物,能够抑制指示剂细菌发光菌的发光。它与金（Ⅲ）和钯（II）形成两种类型的复合物：I型是离子相关联的含有氢键的化合物，II型是含有金属-氧键的六元金属螯合物。

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Isoquinolines 异喹啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinaldines 奎纳丁
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinolines 喹啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinolines 喹啉
  5. C8 to C10 - Quinolines
  1. Functional Group 官能团索引
  2. N-oxide

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