2,4-Dichlorophenol 2,4-二氯酚
CAS 120-83-2 MFCD00002169
化学结构图
SMILES: Oc1ccc(Cl)cc1Cl
化学属性
| Mol. Formula | C6H4Cl2O |
|---|---|
| Mol. Weight | 163 |
| Boiling Point | 209-210 |
| Melting Point | 42-43 |
| Flash Point | 114°(237°F) |
| TSCA | Yes |
| Density | 1.383 |
| Solubility | 4.5 G/L (20 ºC) |
| Stability | 对光敏感 |
| Appearance | melt |
别名和识别编码
| Chemical Name | 2,4-Dichlorophenol |
|---|---|
| CAS Number | 120-83-2 |
| PubChem Substance ID | 8449 |
| EC Number | 204-429-6 |
| Beilstein Registry Number | 742467 |
| MDL Number | MFCD00002169 |
| Reaxys-RN | 742467 |
| Merck Number | 3072 |
| Synonym | 2,4-DICHLOROPHENOL, 5000MG, NEAT 2,4-dichloro-phenol phenol, 2,4-dichloro- 2，4-二氯酚 2,4-Dichlorophenic acid 1-Hydroxy-2,4-dichlorobenzene 4-双氯酚 Isobac 2,4-二氯酚 NCI-C55345 4-二氯苯酚 Phenol,2,4-dichloro- 2,4-dichloro-pheno 2,4-双氯酚 2,4-dlchlorophenol 2,4-DICHLOROPHENOL PESTANAL 2,4-dichloro phenol(DCP) 2 2,4-二氯苯酚 2,4-Dichlorohydroxybenzene Dichlorophenol, 2,4-DCP 2,4-Dichlorphenol 2，4-二氯苯酚 RCRA waste number U081 2,4-dichlorohydroxybenzene rcrawastenumberu081 2,4-Dichlorophenol 4-二氯酚 4,6-dichlorophenol 2,4-DICHLORO-1-HYDROXY-BENZENE |
| Chemical Name Translation | 2,4-二氯酚 |
| Wiswesser Line Notation | QR BG DG |
| LabNetwork Molecule ID | LN00195253 |
| InChI | InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- 2000/60/EC, 500 Series Drinking Water Methods, Alpha Sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, D, DIA - DIC, EPA, Environmental Standards, European Community: ISO, DIN and DL 152, Method 552,
产品应用
- 生化研究。有机合成。气相色谱对比样品。植物生长促进剂。
相关文献及参考
- Short: III/35D2
- Merck: 14,3072 Beilstein: 6,IV,885
- Short: III/20b
- Merck: 14,3072
安全信息
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H302 Harmful if swallowed 吞食有害
- H311 Toxic in contact with skin 皮肤接触中毒
- H300 Fatal if swallowed 吞食致命
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P330+P331+P310
- P303+P361+P353
- P303+P361+P353+P310+P363
- P305+P351+P338
- P308+P311
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- R22 Harmful if swallowed 吞咽有害
- R24 Toxic in contact with skin 与皮肤接触有毒
- R34 Causes burns 会导致灼伤
- R51/53
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16 gm/kg/39W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 7,321,1959/1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1276 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 5,478,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 790 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(10),16,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 430 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature increase REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London,
{TYPE OF TEST : Sex chromosome loss and nondisjunction TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 500 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 333 ug/plate REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-353,1989
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 30 mg/L REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-353,1989
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 200 umol/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 24,181,1994
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 3100 ug/L REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-353,1989
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 666 mg/kg SEX/DURATION : female 6-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB223-160
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 20 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 41(11),102,1976
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 7500 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,635,1989
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 7500 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS :
其他信息
- 用途三:2，4-二氯苯酚主要用作农药和医药中间体。在农药上可合成有机磷杀虫剂丙硫磷、除草剂2，4-滴、2，4-滴丁酯、禾草灵、甲羧除草醚、甲氧除草醚、唑啶草酮(azafenidin)、丙炔恶草酮(oxadiargyl)以及新杀菌剂氰菌胺(fenoxanil)等。医药方面可作为药物硫双二氯酚的重要原料。
- 下游产品:4-氯苯酚 --> 甲羧除草醚 --> 2-氯苯酚 --> 恶草酮 --> 硫氯酚 --> 2,4-二氯苯氧乙酸 --> 三氯生 --> 2,5-二氯苯酚 --> 丙硫磷 -
- 图谱信息:2,4-二氯酚(120-83-
- 毒性分级:中毒
- MSDS 信息:2,4-二氯酚(120-83-2).msds
- 方法一:2，4-二氯苯酚的制备主要有两条路线。 苯酚催化氯化法 由苯酚在铁催化下与氯气作用制得。 将熔融的苯酚抽入氯化罐和吸收罐，加热到50～60℃，通入氯气，氯气先进入氯化罐，再串联进入吸收罐，尾气通入石墨薄膜吸收塔，用水吸收尾气中的氯化氢。反应罐的夹套及盘管通冷却水移出反应热。当氯化罐物料的相对密度达到1.402～1.405(40℃)时为氯化终点，停止通氯气，从氯化罐放出2，4-二氯苯酚。下一批氯化时，原吸收罐作为氯化罐，先通入新鲜氯气，而原氯化罐抽入原料苯酚作为吸收罐使用。 此法为国内企业所采用，生产工艺简单，但反应时间较长，且副产物2，6-二氯苯酚、2，4，6-三氯苯酚沸点相近，分离困难。 邻氯苯酚选择氯化法 用三氯化铝和二苯硫醚作催化剂，用硫酰氯作氯化剂。 此法可利用生产对氯苯酚的副产邻氯苯酚为原料，且反应条件温和，设备要求不高，环境污染少，产品纯度高，但所用催化剂和氯化剂的价格较高。
- 方法二:苯酚在铁催化下通氯气氯化而得。
- TCI Shanghai:2,4-二氯苯酚 2,4-Dichlorophenol,>;98.0%(GC)(120-83-2)
- MOL 文件:120-83-2.mol
- {Chemi
- 储运特性:库房通风低温干燥; 与氧化剂、食品化工添加剂、酸类分开存放
- 用途四:用作农药和医药中间体。用于合成除草醚、2,4-D、伊比磷（EPBP）、毒克散、格螨酯以及药物硫双二氯酚。
- 用途六:用于有机合成。校准仪器和装置；评价方法；工作标准；质量保证/质量控制；其他。
- 可燃性危险特性:明火可燃;受热分解或遇酸放出氯化物气体;与氧化剂起作用
- Alfa Aesa
- 外观性质:无色结晶。
- 用
- 下游产品:4-氯苯酚 --> 甲羧除草醚 --> 2-氯苯酚 --> 恶草酮 --> 硫氯酚 --> 2,4-二氯苯氧乙酸 --> 三氯
- 能随水蒸气挥发。溶于乙醇、乙醚、苯和四氯化碳，微溶于水。低毒，半数致死量(大鼠，经口)580mg/kg。对组织有强烈刺激性。
- Acros Organics:2,4-二氯苯酚 2,4-Dichlorophenol, 99%(120-83-2)
- {C
- 2,4-二氯酚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80047726 2，4-二氯酚 100g 66元 2011/04/16 D3865 2,4-二氯酚[用于生化研究] 2,4-Dichlorophenol [for Biochemical Research] 1G 208元 2011/04/16 D3865 2,4-二氯酚[用于生化研究] 2,4-Dichlorophenol [for Biochemical Research] 5G 520元
- 防护措施:易挥发，腐蚀性强，能灼烧皮肤，刺激眼睛及皮肤。中毒严重者，可产生贫血及各种神经系统症状。对皮肤过敏者，可经起皮炎而难治愈。车间应通风良好，设备应密闭。操作时应戴口罩、眼镜和胶皮手套。如不慎溅及皮肤，应立即用酒精擦洗或用稀碱水冲洗。若已入口，应立即用温水和氧化镁（30g/L）洗胃。飞溅衣服上，立即更换衣服并洗澡，以防渗入皮肤。
- 类别:农药
- 用途二:用于有机合成
京ICP备2020036287号