5,12-Naphthacenedione,7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(chloroacetyl)-1-methoxy-6,8,11-trihydroxy-, (8S-cis)-

CAS 121250-06-4 MFCD00879388

化学结构图

121250-06-4
SMILES: C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2=C(O)C3C(=O)C4C=CC=C(OC)C=4C(=O)C=3C(O)=C21)C(=O)CCl

化学属性

Mol. FormulaC27H28ClNO10
Mol. Weight562.01

别名和识别编码

Chemical Name5,12-Naphthacenedione,7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(chloroacetyl)-1-methoxy-6,8,11-trihydroxy-, (8S-cis)-
CAS Number121250-06-4
Synonym 14-Chlorodaunomycin 8S,10S)-10-[(3-Amino-2,3,6-trideoxy-?-L-lyxo-hexopyranosyl)oxy]-8-(2-chloroacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione 14-Chlorodaunorubicin 14-Chlororubomycin
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Drug Analogues
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Adriamycin analogue; use as anticancer agent.

相关文献及参考

  • Krishan, A., et al.: Cancer Res., 41, 2745 (1981),
  • Mueller, M., et al.: Eur. J. Biochem., 140, 447 (1984),

安全信息

RTECSQI9325500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O Me
   zhdunarodnaya Kniga, 113095 Moskow, USSR)  V.33-    1988-
   Volume(issue)/page/year: 35(2),24,1990

系列性分类

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