Mefexamide Hydrochloride 美非沙胺盐酸盐

CAS 1227-61-8 MFCD00079457

化学结构图

1227-61-8
SMILES: CCN(CC)CCNC(=O)COc1ccc(OC)cc1

化学属性

Mol. FormulaC15H24N2O3
Mol. Weight280.41

别名和识别编码

Chemical NameMefexamide Hydrochloride
MDL NumberMFCD00079457
CAS Number1227-61-8
Synonym ANP 297 Mefexamide 美非沙胺 盐酸盐 MP 297 U-25701A 对-甲氧基苯氧基乙酸 2-(二乙胺基)乙酰胺 N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide Mefaxadyne 2-(p-Methoxyphenoxy)-N-(2-(diethylamino)ethyl)acetamide Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)- NP 297 Timodyne Mephexamide Mexephenamide
PubChem Substance ID4045
EC Number214-963-1
Chemical Name Translation美非沙胺盐酸盐
Wiswesser Line Notation2N2&2MV1OR DO1
Beilstein Registry Number2219009
InChIInChI=1S/C15H24N2O3/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14/h6-9H,4-5,10-12H2,1-3H3,(H,16,18)
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M, MEA - MES, Neat Compounds, 分析/色谱
  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M, MEA - MES, Neat Compounds
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M,

安全信息

RTECSAB7175000
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
WGK Germany3
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S22 Do not breathe dust 不要吸入粉尘；
Hazard Codes T+
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #2702M

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPYAT Annales Medico-Psychologiques.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-Series 11, V.2, 1843-1921; V.80-    1922-
   Volume(issue)/page/year: 123,141,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,444,1966

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Forensic and Veterinary Standards - Chromatography
  5. Drugs & Metabolites - Forensic and Veterinary Standards
  6. Neat Compounds - Drugs & Metabolites
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. M - Alphabetic
  5. MEA - MES - M

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