2,4-Piperidinedione, 3,3-diethyl-5-methyl-

CAS 125-64-4 MFCD00057334

化学结构图

125-64-4
SMILES: CCC1(CC)C(=O)NCC(C)C1=O

化学属性

Mol. FormulaC10H17NO2
Mol. Weight183.28

别名和识别编码

Chemical Name2,4-Piperidinedione, 3,3-diethyl-5-methyl-
Wiswesser Line NotationT6MV DVTJ C2 C2 E1
Synonym Ro 1-6463 3,3-Diethyl-5-methyl-2,4-piperidinedione Dimerin 3,3-Diethyl-5-methylpiperidine-2,4-dione Noctan Methyprylon Metiprilone 2,4-Dioxy-3,3-diethyl-5-methylpiperidine 3,3-Diethyl-2,4-dioxo-5-methylpiperidine Methyprolon Noludar
CAS Number125-64-4
Beilstein Registry Number0082860
PubChem Substance ID4162
InChIInChI=1S/C10H17NO2/c1-4-10(5-2)8(12)7(3)6-11-9(10)13/h7H,4-6H2,1-3H3,(H,11,13)
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安全信息

RTECSTM7350000
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Rectal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 7,513,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,264,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
REFERENCE :
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, se

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 315 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,264,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 890 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than leth

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