Morphinan, 3-methoxy-17-methyl-, l- 消旋甲啡烷

CAS 125-70-2 MFCD00866833

化学结构图

125-70-2
SMILES: COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(C)CC3

化学属性

Mol. FormulaC18H25NO
Mol. Weight271.44

别名和识别编码

Chemical NameDEXTROMETHORPHAN
CAS Number125-70-2
Synonym Methorphan 3-Methoxy-17-methylmorphinan Levomethorphan 1,3,4,9,10,10a-Hexahydro-6-methoxy-11-methyl- l-Methorphan
PubChem Substance ID5362449
InChIInChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m0/s1
Chemical Name Translation消旋甲啡烷
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分类

  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • The enatiomer of Dextromethorphan (D299455), an antitussive medicine, a narcotic.

相关文献及参考

  • Hafliger, et al.: Helv. Chim. Acta, 39, 2053 (1956),
  • Cox, B.M., et al.: Br. J. Pharmacol. Chemother., 27, 81 (1966),
  • Hou, Chia-Hui; Tzeng, J., et al.: Eur. J. Pharmacol., 544, 10 (2006),

安全信息

RTECSQD0193400 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 78 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 17,433,1961

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