Sulfamerazine Sodium 磺胺甲嘧啶钠

CAS 127-58-2 MFCD00068332

化学结构图

127-58-2
SMILES: Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1.[NaH]

化学属性

Mol. FormulaC11H11N4O2SNa
Mol. Weight286.29

别名和识别编码

Chemical NameSulfamerazine Sodium
MDL NumberMFCD00068332
CAS Number127-58-2
Synonym N(sup 1)-(4-Methyl-2-pyrimidinyl)sulfanilamide sodium salt 4-氨基-N-(4-甲基-2-嘧啶基)苯磺酰胺 sulfamerazine sodium SODIUM SULFAMERAZINE solublesulfamerazine 磺胺甲嘧啶钠 2-sulfanilamido-4-methylpyrimidine sodium salt monosodium 2-sulfanilamido-4-methylpyrimidine 4-methyl-2-sulfanilamidopyrimidine sodium salt Sodium sulfamerazine sodiumsulphamerazine 磺胺甲嘧啶 钠盐 磺胺甲基嘧啶钠 n(sup1)-(4-methyl-2-pyrimidinyl)sulfanilamidesodiumsalt solumedine Monosodium 2-sulfanilamido-4-methylpyrimidine; 2-Sulfanilamido-4-methylpyrimidine sodium salt; 4-Methyl-2-sulfanilamidopyrimidine sodium salt; Solumedine n(sup1)-(4-methyl-2-pyrimidinyl)-sulfanilamidmonosodiumsalt SULFAMERAZINE SODIUM SALT 磺胺甲基嘧啶鈉 SULFAMERAZINE, SODIUM SALT MONOHYDRATE Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt Sulfamerazine sodium SulfadimidineSodium,Pharma 4-amino-n-(4-methyl-2-pyrimidinyl)-benzenesulfonamidmonosodiumsalt SULFAMERAZINE SODIUM(SM1-NA)(NDC:56631-1715) 4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE SODIUM SALT Sodium sulphamerazine Solumedine Soluble sulfamerazine
PubChem Substance ID15899899
EC Number204-851-0
Chemical Name Translation磺胺甲嘧啶钠
InChIKeyBSFJGCCAXDCMOX-UHFFFAOYSA-N
Wiswesser Line NotationT6N CNJ BMSWR DZ& D1 &-NA-
InChIInChI=1S/C11H11N4O2S.Na/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10;/h2-7H,12H2,1H3;/q-1;+1
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分类

  • {SNA} Building Blocks, C9 to C11, Chemical Synthesis, Heterocyclic Building Blocks, Pyrimidines

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P317
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H332 Harmful if inhaled 吸入有害
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S24 Avoid contact with skin 避免皮肤接触；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
Hazard Codes Xn
Risk Statements
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
RTECSWP0760000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 94,338,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1522 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,17,1944

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 94,338,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1739 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,17,1944

其他信息

  • MOL 文件:127-58-2.mol
  • Sigma Aldrich:127-58-2(sigmaaldrich)

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrimidines 嘧啶
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrimidines 嘧啶
  5. C9 to C11 - Pyrimidines

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