Sivelestat 西维来司他

CAS 127373-66-4 MFCD00889071

化学结构图

127373-66-4
SMILES: CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC1C=CC=CC=1C(=O)NCC(O)=O

化学属性

Mol. FormulaC20H22N2O7S · xNa+· yH2O
Mol. Weight434.46 (anhydrous free acid basis)

别名和识别编码

Chemical NameSivelestat
Synonym EI 546 sodium salt hydrate Elaspol sodium salt hydrate LY 544349 sodium salt hydrate Ono-5046 sodium salt hydrate o-(p-Hydroxybenzenesulfonamido)hippuric acid, pivalate (ester) sodium salt hydrate
CAS Number127373-66-4 (free acid)
Chemical Name Translation西维来司他
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytoskeleton and Extracellular Matrix, Microtubule Inhibitors, S, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Yuichiro Toda, et al. A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats. Int J Mol Med. 2007 Feb;19(2):237-43.
  • [3]. Tomoharu Kono, et al. Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder. Mol Cell Biochem. 2008 Apr;311(1-2):87-92.
  • [4]. Adeleh Sahebnasagh, et al. Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19. J Clin Pharm Ther. 2020 Aug 28.
  • [1]. Kawabata K, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun. 1991 Jun 14;177(2):814-20.
  • [1]. Kawabata K, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun. 1991 Jun 14;177(2):814-20.
  • [2]. Yuichiro Toda, et al. A neutrophil elastase i

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Elastase  (弹性蛋白酶)

相关产品推荐