3-(4-Chlorophenyl)-N,N-Dimethyl-3-(Pyridin-2-Yl)Propan-1-Amine 3-(4-氯苯基)-N,N-二甲基-3-(吡啶-2-基)丙-1-胺

CAS 132-22-9 MFCD00053581

化学结构图

132-22-9
SMILES: CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1

化学属性

Mol. FormulaC16H19ClN2
Mol. Weight274.82

别名和识别编码

Chemical Name3-(4-Chlorophenyl)-N,N-Dimethyl-3-(Pyridin-2-Yl)Propan-1-Amine
Wiswesser Line NotationT6NJ BYR DG&2N1&1
Synonym Chlorphenamine 2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Chlorophenylpyridamine Chloroprophenpyridamine Chloropiril 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine Allergisan Histadur Cloropiril 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl- Polaronil Chlorprophenpyridamine Clorfeniramina Haynon Allergican Chlorpheniramine 4-Chloropheniramine
CAS Number132-22-9
PubChem Substance ID2725
InChIInChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
LabNetwork Molecule IDLN01344984
Chemical Name Translation3-(4-氯苯基)-N,N-二甲基-3-(吡啶-2-基)丙-1-胺
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安全信息

RTECSUS6379500
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   111,293,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MEWEAC Medizinische Welt.  (F.K. Schattauer Verlag, Postfach 2945, D-7000
   Stuttgart 1, Fed. Rep. Ger.)  V.1-18, 1927-1944; V.1-    1950-
   Volume(issue)/page/year: 17,2791,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 121 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MEWEAC Medizinische Welt.  (F.K. Schattauer Verlag, Postfach 2945, D-7000
   Stuttgart 1, Fed. Rep. Ger.)  V.1-18, 1927-1944; V.1-    1950-
   Volume(issue)/page/year: 17,2791,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSUR

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 92,1339,197

系列性分类


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