(1R,2S)-(-)-Ephedrine hydrochloride dl-ephedrine

CAS 134-71-4 MFCD00012626

化学结构图

134-71-4
SMILES: CN[C@H](C)[C@@H](O)c1ccccc1.Cl

化学属性

Mol. FormulaC6H5CH(OH)CH(CH3)NHCH3· HCl
Mol. Weight201.69
Melting Point188-190 °C

别名和识别编码

Chemical Namehydrochloride rac-Ephedrine Hydrochloride
CAS Number50-98-6
Synonym DL-EPHEDRINE HYDROCHLORIDE ephetonine hydrochloride,(+-)-ephedrin alpha-[1-(methylamino)ethyl]benzyl alcohol hydrochloride 消旋盐酸麻黄碱 Altusin dl-α-[1-(Methylamino)ethyl]benzyl Alcohol Hydrochloride 麻黄素 麻黄碱 盐酸盐 (R*,S*)-(+/-)-alpha-[1-(Methylamino)ethyl]benzyl alcohol hydrochloride (+/-)-Ephedrine Hydrochloride Benzenemethanol, α-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (αS)-rel- dl-?-[1-(Methylamino)ethyl]benzyl Alcohol Hydrochloride dl-Ephedrine HCl (?S)-rel-?-[(1R)-1-(Methylamino)ethyl]benzenemethanol Hydrochloride (+/-)-2-Ephedrinium Hydrochloride ephetonin dl-alpha-(1-(methylamino)ethyl)benzylalcoholhydrochloride benzenemethanol,alpha-[1-(methylamino)ethyl]-,hydrochloride,(theta,s)-(+/-) Benzenemethanol, α-[1-(methylamino)ethyl]-, hydrochloride, (R*,S*)-(+-)- 1-phenyl-2-methylaminopropanol-1 DL-erythro-Ephedrine hydrochloride 左旋盐酸麻黄碱 racephedrinehydrochloride (1R,2S)-2-甲氨基-苯丙烷-1-醇盐酸盐 Benzenemethanol, alpha-(1-(methylamino)ethyl)-, hydrochloride, DL-A-(1-METHYLAMINOETHYL)BENZYL ALCOHOL HYDROCHLORIDE DL-ephedrine hydrochloride(BP98) (1R,2S)-α-[1-(甲氨基)乙基]苄醇 盐酸盐 (1R,2S)-(-)-2-甲氨基-1-苯丙醇 盐酸盐 (1R,2S)-(?)-麻黄碱 盐酸盐 Benzenemethanol, α-[1-(methylamino)ethyl]-, hydrochloride, (R*,S*)- EPHEDRINE HYDROCHLORIDE DL-盐酸麻黄碱 盐酸麻黄碱 (±)-麻黄素盐酸盐 (r*,s*)-(+/-)-alpha-[1-(methylamino)ethyl]benzyl alcohol hydrochloride (±)-麻黄碱盐酸盐
MDL NumberMFCD00012626
PubChem Substance ID8648
EC Number205-153-9
Beilstein Registry Number3630391
Chemical Name Translationdl-ephedrine
Merck Number13,3639
Wiswesser Line NotationQYR&Y1&M1 &GH -L
InChIInChI=1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Alkaloid, Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds, Phytochemicals by Chemical Classification, 细胞生物学, 营养研究
  • Amines
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Auxiliaries, Ephedrine Derivatives
  • Aromatics

产品应用

  • ?- and ?-Adrenergic agonist. Bronchodilator.

相关文献及参考

  • Duddu, S., et al.: Pharm. Res., 11, 1549 (1994),

安全信息

WGK Germany3
GHS Symbol
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSKB1750000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xn
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S25 Avoid contact with eyes 避免眼睛接触；
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Packing GroupIII
Hazard Class6.1(b)
UN Number 1544
Restrict 易制毒化学品 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intradermal
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5700 ng/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 76,295,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40870 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 87,214,1946

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 95,336,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 95 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 95,336,1949

TYPE OF TEST            : LDLo

其他信息

  • 用途一:用于预防支气管哮喘和缓解轻度哮喘等。
  • Sigma Aldrich:134-71-4(sigmaaldrich)
  • MOL 文件:134-71-4.mol

系列性分类

  1. Life Science 生命科学
  2. Nutrition Research 营养研究
  3. Phytochemicals by Chemical Classification - Nutrition Research
  4. Alkaloid - Phytochemicals by Chemical Classification
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Auxiliaries - Asymmetric Synthesis
  4. Ephedrine Derivatives - Chiral Auxiliaries
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Oxygen Compounds 氧化合物
  5. Amino Alcohols - Oxygen Compounds

相关产品推荐