1,4-bis[(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methoxy]phthalazine 氢化奎尼定1,4-(2,3-二氮杂萘)二醚

CAS 140853-10-7 MFCD00198107

化学结构图

140853-10-7
SMILES: COC1=CC2C(=CC=NC=2C=C1)[C@H](OC1=NN=C(O[C@H]([C@H]2C[C@@H]3CCN2C[C@@H]3CC)C2=CC=NC3C=CC(=CC=32)OC)C2C=CC=CC=21)[C@H]1C[C@@H]2CCN1C[C@@H]2CC

化学属性

Mol. FormulaC48H54N6O4
Mol. Weight778.98
Melting Point160
Density1.3

别名和识别编码

Chemical Name1,4-bis[(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methoxy]phthalazine
MDL NumberMFCD00198107
Synonym (DHQD)2PHAL AD-mix-beta 氢化奎尼定 1,4-(2,3-二氮杂萘)二醚 氢化奎尼定1,4-(2,3-二氮杂萘)二醚;(DHQD)2PHAL
PubChem Substance ID329755836
Beilstein Registry Number5475678
CAS Number140853-10-7
Chemical Name Translation氢化奎尼定1,4-(2,3-二氮杂萘)二醚
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Asymmetric Synthesis, Chemical Reagents, Chemical Synthesis, Chiral Catalysts, Ligands, and Reagents, Cinchona Alkaloids, Development Quantities for Research, Dihydroxylation, Privileged Ligands and Complexes
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Catalysts, Ligands, and Reagents, Cinchona Alkaloids, Dihydroxylation, Privileged Ligands and Complexes
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Catalysts, Ligands, and Reagents, Cinchona Alkaloids, Dihydroxylation, Greener Alternative Products, Privileged Ligands and Complexes, Re-engineered Products
  • Asymmetric Synthesis, Chemical Synthesis,

产品应用

  • 配体，用于非对称氢化反应。

相关文献及参考

  • 1. J. Org. Chem. 71 , 7741, (2006) 摘要
  • 2. Eur. J. Org. Chem. , 2669, (2006)
  • Chem. Rev. 94 , 2483, (1994)
  • J. Org. Chem. 57 , 2768, (1992)

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard Codes Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R32 Contact with acids liberates very toxic gas 与酸接触释放出毒性很高的气体
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Catalysts, Ligands, and Reagents - Asymmetric Synthesis
  4. Dihydroxylation - Chiral Catalysts, Ligands, and Reagents
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Catalysts, Ligands, and Reagents - Asymmetric Synthesis
  4. Privileged Ligands and Complexes - Chiral Catalysts, Ligands, and Reagents
  5. Cinchona Alkaloids - Privileged Ligands and Complexes
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Catalysts, Ligands, and Reagents - Asymmetric Synthesis
  4. Privileged Ligands and Complexes - Chiral Catalysts, Ligands, and Reagents
  5. Cinchona Alkaloids - Privileged Ligands and Complexes
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Catalysts, Ligands, and Reagents - Asymmetric Synthesis
  4. Chiral Ligands

相关产品推荐