Biotin-bis-amido-SS-NHS Biotin-bis-amido-SS-NHS

CAS 142439-92-7 MFCD00466919

化学结构图

142439-92-7
SMILES: O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)NCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

化学属性

Mol. FormulaC22H33N5O7S3
Mol. Weight576

别名和识别编码

Chemical NameBiotin-bis-amido-SS-NHS
Synonym (2-[Biotinamido]ethylamido)-3,3′-dithiodipropionic acid N-hydroxysuccinimide ester (2-[Biotinamido]ethylamido)-3,3'-dithiodipropionic acid N-hydroxysuccinimide ester
MDL NumberMFCD00466919
PubChem Substance ID24891785
CAS Number142439-92-7
Chemical Name TranslationBiotin-bis-amido-SS-NHS
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分类

  • {SNA} Biotinylation, Protein Modification, Reagents for Biotinylating Amines, 分子生物学, 蛋白质组学, 蛋白质结构分析
  • Biotinylation, Protein Modification, Protein Structural Analysis, Proteomics, Reagents for Biotinylating Amines
  • {SNA} Biotinylation, Protein Modification, Protein Structural Analysis, Proteomics, Reagents for Biotinylating Amines

相关文献及参考

  • Mouton, C.A., et al., A reagent for covalently attaching biotin to proteins via a cleavable connector arm. Arch. Biochem. Biophys. 218 , 101-108, (1982) 摘要
  • Lomant, A.J. and Fairbanks, G., Chemical probes of extended biological structures: synthesis and properties of the cleavable protein cross-linking reagent [35S]dithiobis (succinimidyl propionate). J. Mol. Biol. 104 , 243-261, (1976) 摘要
  • Ichikawa, M., and Ichikawa, Y., A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase. Bioorg. Med. Chem. Lett. 11 , 1769-1773, (2001) 摘要
  • Engert, A., et al., A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin’s lymphoma patients treated with an anti-CD25 immunotoxin Clin. Exp. Immunol. 136 , 365-372, (2004) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Signal word Danger
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Hazard Codes T
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
Risk Statements
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害

系列性分类

  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Biotinylation - Protein Modification
  6. Reagents for Biotinylating Amines - Biotinylation
  1. Functional Group 官能团索引
  2. disulfide

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