Phenol red 酚红

CAS 143-74-8 MFCD00003552

化学结构图

143-74-8
SMILES: [O-]S1([O-])OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

化学属性

Mol. FormulaC19H14O5S
Mol. Weight354.38
TSCAYes
Boiling Point>300 °C at 760 mmHg
Melting Point>300 °C
SolubilityPractically insoluble in chloroform, ether. Soluble in aqueous alkali hydroxides or carbonates with red color (removed by boiling with zinc dust). Solubility in water: approximately 1g/1300ml. Solubility in alcohol: approximately 1g/350ml
Density1.477
Flash Point>300°C
Appearance 深红色结晶性粉末。1g本品溶于1300ml水,约350ml醇,500ml丙酮,几乎不溶于醚和氯仿,溶于氢氧化碱或碳酸碱溶液中呈深红色,在空气中稳定。

别名和识别编码

Chemical NamePhenol red
MDL NumberMFCD00003552
PubChem Substance ID87574854
CAS Number143-74-8
Reaxys-RN326470
Beilstein Registry Number19(3/4)1128
Merck Number7247
Synonym Phenol Red {LY} Phenol Red {} {LY} Phenol Red {} {} {LY} Phenol Red {} {} {} {LY} Phenol Red {} {} {} {} {LY} Phenol Red {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {}
EC Number205-609-7
Chemical Name Translation酚红
Wiswesser Line NotationT56 BSWO DHJ DR DQ& DR DQ
LabNetwork Molecule IDLN00194920
InChIInChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
Canonical SMILESO=S1(OC(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)C4=CC=CC=C41)=O
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分类

  • {SNA} Indicators, Titration,
  • In Vivo/In Vitro Tracking of Stem Cells, Assays and Reagents for Measuring Cytotoxicity, Proliferation and Viability, Cell Biology, Cell Culture, Cell Culture Supplies, Cell Staining for Scale-Up Cell Culture, Core Bioreagents, General Stains/Dyes for Stem Cell Biology, General Stem Cell Biology, Hematology and Histology, Labware, Life Science Reagents for Cell Culture, P, Reagents and Supplements, Research Essentials, Scale-Up Cell Culture using Corning Roller Bottles, Stains & Dyes, Stains & Dyes, A to Z, Stains and Dyes, Stains, Dyes and Indicators, Stem Cell Biology, Stem Cell Characterization
  • {SNA} In

产品应用

  • 酸碱指示剂,变色范围pH:6.8(黄)-8.4(红)。血液二氧化碳全量测定,细菌血清检验中制备双糖铁尿素培养基的指示剂。其钠盐用于测定肝功能。

相关文献及参考

  • Merck: 14,7247 Beilstein: 19,V,3,457
  • Merck: 14,7247
  • Acid-base indicator: approx pH 6.8 - 8.2.

安全信息

WGK Germany3
Signal word
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSSJ7490000
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
GHS Symbol
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition RT, protect from light {LY} RT, protect from light Store at RT. {} {LY} RT, protect from light {} {} {LY} RT, protect from light {} {} {} {LY} RT, protect from light {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect fr
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 4(2),185,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1368 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,930,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 752 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,930,1990

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   AEMIDF Applied and Environmental Microbiology.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.31-    1976-
   Volume(issue)/page/year: 42,641,1981

其他信息

  • MSDS 信息:Phenolsulfonephthalein(143-74-8).msds
  • 酚红价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 71032460 酚红;苯酚磺酰酞; 苯酚磺酞; 苯酚红 25g 30元 2011/04/16 P0101 酚红(0.04%的水溶液)[用于pH值检测] Phenol Red (0.04% in Water) [for pH Determination] 500ML 377元 2011/04/16 P0100 酚红 Phenol Red 25G 426元
  • 下游产品:溴酚蓝
  • 用途二:酸碱指示剂,变色范围pH:6.8(黄)-8.4(红)。血液二氧化碳全量测定,细菌血清检验中制备双糖铁尿素培养基的指示剂。其钠盐用于测定肝功能。
  • 用途一:用作酸碱指标剂,变色范围pH:6.8(磺)-8.4(红)。也用于生化研究。
  • Acros Organics:苯酚红/酚红 分析级别 Phenol Red, conform to ACS, pure(143-74-8)
  • 方法一:将邻磺基苯甲酸酐与苯酚共热熔化,加入无水氯化锌于135-140℃反应7h,然后将缩合物倒入热水中,用滤,用水洗涤固体,进一步用酸碱沉淀法提纯而得成品。
  • 图谱信息:酚红(143-74-8)质谱(MS) 酚红(143-74-8)红外图谱(IR1) 酚红(143-74-8)红外图谱(IR2)
  • Alfa Aesar:苯酚红,ACS Phenol Red, ACS(143-74-8)
  • 上游原料:氯化锌 --> 2-磺基苯甲酸酐
  • TCI Shanghai:酚红(0.1%的乙醇(约20%)溶液)[用于滴定] Phenol Red (0.1% in ca. 20% Ethanol) [for Titration](143-74-8)
  • MOL 文件:143-74-8.mol
  • 1g本品溶于1300ml水,约350ml醇,500ml丙酮,几乎不溶于醚和氯仿,溶于氢氧化碱或碳酸碱溶液中呈深红色,在空气中稳定。
  • 海关编码:29349990
  • Sigma Aldrich:143-74-8(sigmaaldrich)

系列性分类