Iodonitrotetrazolium chloride 碘硝基氯化四氮唑
CAS 146-68-9 MFCD00011961
化学结构图
SMILES: O=[N+]([O-])c1ccc(-[n+]2nc(-c3ccccc3)nn2-c2ccc(I)cc2)cc1.[Cl-]
化学属性
| Mol. Formula | C19H13ClIN5O2 |
|---|---|
| Mol. Weight | 505.70 g/mol |
| Melting Point | 240-245 |
| Solubility | Soluble in water (4 mg/ml), ethanol (8 mg/ml), ethylene glycol (30 mg/ml), DMSO (slightly), and methanol: water (1:1, 50 mg/ml, very faintly turbid, very deep yellow,hot). |
| Stability | 易吸潮,对热及光线敏感 |
别名和识别编码
| Chemical Name | Iodonitrotetrazolium chloride |
|---|---|
| Synonym | 2-(4-IODOPHENYL)-3-(4-NITROPHENYL)-5-PHENYLTETRAZOLIUM CHLOR 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride iodonitrotetrazolium iodonitrotetrazolium violet {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {JNK} p-Iodonitrotetrazolium Violet {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} iodonitrotetrazolium violet {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} |
| MDL Number | MFCD00011961 |
| PubChem Substance ID | 64957 |
| Beilstein Registry Number | 4093224 |
| CAS Number | 146-68-9 |
| EC Number | 205-676-2 |
| Reaxys-RN | 3846329 |
| Chemical Name Translation | 碘硝基氯化四氮唑 |
| InChI | InChI=1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1 |
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分类
- {SNA} Biochemicals and Reagents, Enzyme Substrates, Histidinol Dehydrogenase, Ketolisomerase, Lactic Dehydrogenase, Lactyl-CoA Dehydrogenase, Oxidase, Peroxidase Substrates,
- {SNA} Core Bioreagents,
- {SNA} Enzyme Substrates
- {SNA} Enzyme Substrates, Histidinol Dehydrogenase, Ketolisomerase, Lactic Dehydrogenase, Lactyl-CoA Dehydrogenase, Oxidase, Peroxidase Substrates, Substrates by Enzyme, Succinic dehydrogenase, Xanthine dehydrogenase, 生化试剂, 酶、抑制剂和底物
- {SNA} Core Bioreagents, G-H-I, Research Essentials, Stains & Dyes, A to Z, Stains and Dyes,
产品应用
- 色度法检测各种脱氢酶的电子受体（Electron acceptor）
相关文献及参考
- 1. Toxic Asses. 3 , 41, (1988)
- M.N. Nachlas, lactate dehydrogenase. Anal. Biochem. 1 , 317, (1960)
- A.L. Babson, S.R. Babson Clin. Chem. 19 , 766, (1973)
- R. Fried, xanthine dehydrogenase. Anal. Biochem. 16 , 427, (1966)
- R.L. Baldwin, W.A. Wood, lactyl-CoA dehydrogenase. Meth. Enzymol. 9 , 683, (1966) 摘要
- D.J. Morré, succinate dehydrogenase. Meth. Enzymol. 22 , 130, (1971)
- R.G. Martin, BBM II ketolisomerase and histidinol dehydrogenase. Meth. Enzymol. 17B , 3, (1971)
- Beil. 26 ,IV,1776
- FT-IR 2 (3), 3537:C / FT-IR 1 (2), 634:A / FT-NMR 1 (3), 95:B / IR-Spectra (3), 1228:B / IR-Spectra (2), 1068:E / NMR-Reference 2 (2), 502:C / RegBook 1 (2), 2373:F / Sigma FT-IR 1 (2), 661:C / Stains and Dyes Ref , 410 / Structure Index 1 , 376:C:7
安全信息
- H228 Flammable solid 易燃固体
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H332 Harmful if inhaled 吸入有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H371 May cause damage to organs 可能导致器官损伤
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P264+P265
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312+P330
- P301+P317
- P302+P352
- P302+P352+P332+P313+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P307+P311
- P317
- P319
- P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
- P330 Rinse mouth. 漱口
- P332+P313
- P332+P317
- P337+P317
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- P362+P364
- P370+P378
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
GHS Symbol
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- S22 Do not breathe dust 不要吸入粉尘；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- R11 Highly flammable 非常易燃
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R68/20/21/22
其他信息
- 用途一:色度法检测各种脱氢酶的电子受体（Electron acceptor）
- MOL 文件:146-68-9.mol
- MSDS 信息:2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride(146-68-9).msds
- 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 I0067 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride 5G 1630元 2014/06/02 I0067 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride 1G 541元 2014/06/02 I0781 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基四唑氯 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride [for Biochemical Research] 100MG 279元
- Iodonitrotetrazolium chloride is an electron acceptor used in various colorimetric assays. The chemical has been mainly documented for its measurement of dehydrogenase activity. In the assay to measure SDH (succinate dehydrogenase) activity, Iodonitrotetrazolium chloride was used as an oxidizing agent being reduced by succinate dehydrogenase. Upon reduction the compound forms a formazan dye measured at 500 nm. Iodonitrotetrazolium chloride has also been used to study the electron transport activity in soils, sediments, and pure enzyme cultures as well as nucleotide diphosphate kinase activity.
- 存储注意事项:光敏感;惰性气体保护
- Acros Organics:2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate, 99%(146-68-9)
- TCI Shanghai:2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride,>;98.0%(T)(146-68-9)
- 检测方法:Titration
- 图谱信息:2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑(146-68-9)红外图谱(IR1) 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑(146-68-9)质谱(MS) 2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑(146-68-9)红外图谱(IR2)
- F:3-8-10
- Alfa Aesar:2-(对碘苯基)-3-(对硝基苯基)-5-苯基四唑氯水合物 Iodonitrotetrazolium violet, 95%(146-68-9)
- 溶于水
- 敏感性:Light
- Sigma Aldrich:146-68-9(sigmaaldrich)
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