{SNA} Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, PPAR and RXR Regulators
Retinoids,
Intermediates & Fine Chemicals
{SNA} Bioactive Small Molecule Alphabetical Index, Gene Regulation and Expression, L, PPAR and RXR Regulators, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
产品应用
LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).
相关文献及参考
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[3]. Martine Cao,et al.The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice. Cancer Prev Res (Phila). 2016 Jan;9(1):105-14.
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[1]. M F Boehm, et al. Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells. J Med Chem
[1]. M F Boehm, et al. Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells. J Med Chem
[2]. D S Lala, et al. Activation of Specific RXR Heterodimers by an Antagonist of RXR Homodimers.Nature. 1996 Oct 3;383(6599):450-3.