α-Chloralose α-氯醛糖

CAS 15879-93-3 MFCD00005542

化学结构图

15879-93-3
SMILES: OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

化学属性

Mol. FormulaC8Cl3H11O6
Mol. Weight310
Density1.773
Melting Point182-184
TSCAYes
Solubility溶于热水、乙醚,微溶于冷水、乙醇、氯仿。

别名和识别编码

Chemical Nameα-Chloralose
Synonym (R)-1,2-O-(2,2,2-TRICHLOROETHYLIDENE)-A-D-GLUCOFURANOSE (R)-1,2-O-(2,2,2-Trichloroethylidene)-alpha-D-glucofuranose 1,2-O-(2, 1,2-O-(2,2,2-TRICHLOROETHYLIDENE)-D-GLUCOFURANOSE 1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose;Anhydro-D-glucochloral 1,2-O-(2,2,2-三氯亚乙基)-α-D-呋喃(型)葡萄糖 Anhydro-D-glucochloral 氯醛糖 1,2-O-[2,2,2-TRICHLOROETHYLIDENE]-ALPHA-D-GLUCOFURANOSE ANHYDROGLUCOCHLORAL Alfamat Alphachloralose CHLORALOSE, A- Chloralose GLUCOCHLORAL Monotrichlor-aethyliden-alpha-glucose Murex alpha-D-Glucochloralose alpha-三氯乙醛化葡萄糖 alpha-氯醛糖 {} {} {} {} {Chemi Α-氯醛糖 α-三氯乙醛化葡萄糖 氮醛糖 氯醛葡糖 氯醛葡糖;糖缩氯醛;1,2-O-(2,2 灭雀灵 糖缩氯醛
MDL NumberMFCD00005542
PubChem Substance ID87565263
Beilstein Registry Number85418
CAS Number15879-93-3
EC Number240-016-7
Reaxys-RN85418
Merck Number2072
Chemical Name Translationα-氯醛糖
Wiswesser Line NotationT5O CO BHJ BXGGG DYQYQYQ1Q
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分类

  • Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Avicides, C, CH, Chemical Class, Chloro, Chromatography, Environmental Standards, Halogenated, Others, Pesticides, Pesticides & Metabolites, Rodenticides
  • {SA} Analytical Standards, Analytical/Chromatography, Avicides, Biochemicals and Reagents, Carbohydrate Chemistry, Carbohydrate Derivatives, Carbohydrates, Chemical Biology, Chemical Synthesis, Chromatography,
  • {SNA} Carbohydrate Chemistry,
  • {SNA} Carbo
  • {SN

产品应用

  • 针对实验室动物,用作麻醉剂。

相关文献及参考

  • Merck 14 ,2072
  • Merck:14,2072 Beilstein: 19,IV,4906

安全信息

RTECSFM9450000
GHS Symbol
WGK Germany1
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Warning {} {} {} {} {} {} {} {TCI}
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310+P330
  • P301+P312+P330
  • P304+P340+P312
  • P305+P351+P338
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Packing GroupIII
Hazard Class6.1
UN Number 3249 2811
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 215 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

{

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Cardiac - other changes
REFERENCE :
   RMVEAG Recueil de Medecine Veterinaire.  (Masson Pub. USA, Inc., Year Book
   Medical Pub., 35 E. Wacker Dr., Chicago IL 60601)  V.1-    1824-
   Volume(issue)/page/year: 154,137,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 31600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF T

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Bird - domestic
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A012,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTCEEM Journal de Toxicologie Clinique et Experimentale.  (SPPIF, B.P.22,
   F-41353 Vineuil, France) V.5-    1985-  Volume(issue)/page/year:
   6(3),175,19

TYPE OF TEST

其他信息

  • TCI Shanghai:α-氯醛糖(含β-异构体) alpha-Chloralose (contains beta-isomer),>;85.0%(GC)(15879-93-3)
  • 比旋光度:18 ° (c=2, 95% C2H5OH)
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 急性毒性:口服- 大鼠 LD50: 400 毫克/ 公斤; 口服- 小鼠 LD50: 200 毫克/ 公斤
  • 类别:农药
  • MOL 文件:15879-93-3.mol
  • alpha-氯醛糖价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 C0074 α-氯醛糖(含β-异构体) alpha-Chloralose (contains beta-isomer) 25G 320元 2010/06/21 147795000 alpha-氯醛糖 alpha-Chloralose 97% 500 GR 1857元 2010/06/21 147791000 alpha-氯醛糖 alpha-Chloralose 97% 100 GR 455元
  • MSDS 信息:α-氯醛糖(15879-93-3).msds
  • 毒性分级:高毒
  • 水中溶解度:1 g/225 ml (15 C),醇溶解度:1g/15ml alcohol (25 C),溶于醚和冰乙酸,微溶于氯仿,不溶于石油醚。
  • 图谱信息:alpha-氯醛糖(15879-93-3)红外图谱(IR2) alpha-氯醛糖(15879-93-3)红外图谱(IR1) alpha-氯醛糖(15879-93-3)质谱(MS)
  • 外观性质:白色结晶粉末。
  • 灭火剂:干粉、泡沫、砂土
  • 可燃性危险特性:燃烧产生有毒氯化物气体
  • Sigma Aldrich:15879-93-3(sigmaaldrich)
  • Acros Organics:alpha-氯醛糖 alpha-Chloralose, 97%(15879-93-3)
  • Alfa Aesar:α-氯醛糖,98+%,^banomerca15% alpha-Chloralose, 98+%, beta anomer ca 15%(15879-93-3)
  • 用途一:针对实验室动物,用作麻醉剂。

系列性分类


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