Erythrosin B 赤藓红B

CAS 16423-68-0 MFCD00144257

化学结构图

16423-68-0
SMILES: [Na+].[Na+].[O-]C(=O)c1ccccc1-c1c2cc(I)c(=O)c(I)c2oc2c1cc(I)c([O-])c2I

化学属性

Mol. FormulaC20H6I4Na2O5
Mol. Weight880
TSCAYes
Stability对光敏感
SolubilitySoluble in water, and alcohol.

别名和识别编码

Chemical NameErythrosin B
MDL NumberMFCD00144257
CAS Number16423-68-0
Synonym 2',4',5',7'-Tetraiodofluorescein disodium salt 2',4',5',7'-Tetraiodofluorescein disodium salt Acid Red 51 Iodoeosin 2’ 7’-四碘荧光素二钠 Acid Red 51 Aizen erythrosine C.I. 45430 Calcocid erythrosine N Iodoeosin Iodoeosine Sodium Salt 四碘荧光素钠盐(赤藓红B) 润滑剂X-1 藻红B,螺异苯并呋喃-1(3H),9'-[9H]占吨-3-酮-3',6'-二羟基-2',4',5',7'-四碘代二钠盐 藻红B钠盐,赤藓红B, 润滑剂X-1,N,N'-亚乙基双硬脂酰胺,藻红,藻红B,酸性地衣红,2’,4’,5’,7’-四碘荧光素二钠 赤藓红 赤藓红,藻红B钠盐 酸性地衣红 酸性红 51;赤藓红
Beilstein Registry Number1443945
PubChem Substance ID329756903
EC Number240-474-8
Reaxys-RN3583865
Merck Number3693
Chemical Name Translation赤藓红B
InChIKeyIINNWAYUJNWZRM-UHFFFAOYSA-L
Wiswesser Line NotationT C666 BO EVJ DI FI IR BVQ& LI MQ NI &-NA- 2
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分类

  • {SNA} Adsorption Indicators, E-F, Indicators, Stains & Dyes, A to Z, Stains and Dyes, Titration, 分析/色谱, 分析试剂, 细胞生物学, 血液学和组织学
  • {SNA} Certified Stains & Dyes,
  • {SNA} Additional Standards, All alphabetical sorted, Analytical Standards, Chromatography, Colorant Standards, Colors, E numbers (Food Additives), E100–E199 (color additives), E127, Food & Beverage Standards,
  • {SNA} Additional Standards,
  • {SNA} Certified Stains & Dyes, E-F, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学,

产品应用

  • 沉淀滴定的吸附指示剂。酸碱滴定荧光指示剂,pH大于2.5无荧光,pH不小于4.0呈浅绿色荧光。光度测定试剂。生物染色剂。

相关文献及参考

  • Merck: 14,3693 Beilstein: 19,V,6,466
  • Merck: 14,3693

安全信息

Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H302 Harmful if swallowed 吞食有害
GHS Symbol
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSLM5950000
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
Hazard Codes Xn
Precautionary statements
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition Light Sensitive & Hygroscopic 充氩保存 密封阴凉干燥避光保存。
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1798 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Endocrine - thyroid tumors
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   25,723,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 47,39,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1264 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EAPHA6 Eastern Pharmacist.  (507, Ashok Bhawan, 93, Neru Place, New Delhi
   110 019, India) V.1-    1958-  Volume(issue)/page/year: 24,125,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1840 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 47,39,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 9,127,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Ro

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 umol/L
REFERENCE :
   SKEZAP Shokuhin Eiseigaku Zasshi.  Food Hygiene Journal.  (Nippon Shokuhin
   Eisei Gakkai c/o Shokuhin Eisei Senta, 2-6-1 Jingumae, Shibuya-ku, Tokyo
   150, Japan)  V.1-    1960-  Volume(issue)/page/year: 12,298,1971

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 120 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 189,223,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 138,153,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 206,171,1988

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 300 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 205,415,1988

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB

{hazard_com}

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 482 gm/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   28,813,1990

其他信息

  • 溶于水溶液呈樱红色,溶于乙醇。加盐酸于水液中析出黄棕色沉淀,加氢氧化钠生成红色沉淀,但能溶于过量试剂中。最大吸收波长(水中)524nm、(95%乙醇中)531nm。低毒,半数致死量(大鼠,经口)2559mg/kg。
  • 溶于水溶液呈樱红色,溶于乙醇。加盐酸于水液中析出黄棕色沉淀,加氢氧化钠生成红色沉淀,但能溶于过量试剂中。最大吸收波长(水中)524nm、(95%乙醇中)531nm。低毒,半数致死量(大鼠,经口)2558mg/kg。
  • 溶于水溶液呈樱红色,溶于乙醇。加盐酸于水液中析出黄棕色沉淀,加氢氧化钠生成红色沉淀,但能溶于过量试剂中。最大吸收波长(水中)524nm、(95%乙醇中)531nm。低毒,半数致死量(大鼠,经口)2560mg/kg。
  • Erythrosin B sodium salt is certified for use in the Jackson stain for plant anatomy, Kreyberg's method for keratin and mucus, and as a counterstain for alum hematoxylin.

系列性分类


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