1H-Indole-5-carboxamide 1H-吲哚-5-甲酰胺

CAS 1670-87-7 MFCD07779486

化学结构图

1670-87-7
SMILES: NC(=O)c1ccc2[nH]ccc2c1

化学属性

Mol. FormulaC9H8N2O
Mol. Weight160.18
Melting Point159-163°C
Boiling Point457.6°C at 760 mmHg
Flash Point230.5°C

别名和识别编码

Chemical Name1H-Indole-5-carboxamide
CAS Number1670-87-7
Synonym SD-169 {LY} SD-169 SD-282 SD282 cpd indole-5-carboxamide {} {LY} SD-169 {} {} {LY} SD-169 {} {} {} {LY} SD-169 {} {} {} {} {LY} SD-169 {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} SD-169 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD07779486
PubChem Substance ID14973220
Chemical Name Translation1H-吲哚-5-甲酰胺
LabNetwork Molecule IDLN01294519
InChIInChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
Canonical SMILESO=C(C1=CC2=C(NC=C2)C=C1)N
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分类

  • {SNA} Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles
  • Heterocycles
  • Indole Derivatives
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics
  • Protein Kinase Inhibitors and Activators

产品应用

  • 1H-Indole-5-carboxamide (SD-169) is a p38? MAPK-selective inhibitor. 1H-Indole-5-carboxamide (SD-169) prevents the development and progression of diabetes in nonobese diabetic (NOD) mice by inhibiting

相关文献及参考

  • Medicherla, S. et al.: J. Pharmacol. Exp. Therap., 318, 99 (2006);

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. S - Bioactive Small Molecules
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indoles 吲哚
  5. C7 to C9 - Indoles

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