2-Amino-5-Nitrobenzophenone 2-氨基-5-硝基二苯甲酮

CAS 1775-95-7 MFCD00007364

化学结构图

1775-95-7
SMILES: Nc1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1

化学属性

Mol. FormulaC13H10N2O3
Mol. Weight242.23
Melting Point159-164°C
TSCANo
Solubility3 MG/L (20 C)
Density1.333
Appearance 淡黄色结晶粉末，熔点 159-164°C,水溶性 3 mg/L (20℃)
Boiling Point478.1°C at 760 mmHg
Flash Point242.9°C

别名和识别编码

Chemical Name2-Amino-5-Nitrobenzophenone
CAS Number1775-95-7
Synonym 2-Amino-5-nitrobenzophenone {LY} 2-Amino-5-nitrobenzophenone 2-amino-5-nitrobenzophenone {} {LY} 2-Amino-5-nitrobenzophenone {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-nitrobenzophenone
MDL NumberMFCD00007364
PubChem Substance ID15681
EC Number217-207-9
Reaxys-RN748830
Beilstein Registry Number748830
Chemical Name Translation2-氨基-5-硝基二苯甲酮
InChIKeyPZPZDEIASIKHPY-UHFFFAOYSA-N
LabNetwork Molecule IDLN00223304
InChIInChI=1S/C13H10N2O3/c14-12-7-6-10(15(17)18)8-11(12)13(16)9-4-2-1-3-5-9/h1-8H,14H2
Canonical SMILESO=C(C1=CC([N+]([O-])=O)=CC=C1N)C2=CC=CC=C2
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品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Building Blocks, C13 to C14, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
  • {SNA} Building Blocks, C13 to C14, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks

产品应用

  • 用作医药中间体。

相关文献及参考

  • Seno, H., et al.: J. Anal. Toxicol., 15, 21
  • Beilstein:14,79

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
RTECSPC4935000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BMEMDK Biological Memoirs.  (International Publishers, C 131, Mahanagar,
   Lucknow 226 006, India) V.1-    1976-  Volume(issue)/page/year: 11,192,1985

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 图谱信息:2-氨基-5-硝基二苯甲酮(1775-95-7)质谱(MS) 2-氨基-5-硝基二苯甲酮(1775-95-7)红外图谱(IR2) 2-氨基-5-硝基二苯甲酮(1775-95-7)核磁图( 1 HNMR) 2-氨基-5-硝基二苯甲酮(1775-95-7)核磁图( 13 CNMR) 2-氨基-5-硝基二苯甲酮(1775-95-7)Raman光谱 2-氨基-5-硝基二苯甲酮(1775-95-7)红外图谱(IR1)
  • MSDS 信息:2-Amino-5-nitrobenzophenone(1775-95-7).msds
  • Sigma Aldrich:1775-95-7(sigmaaldrich)
  • 用途一:用作医药中间体。
  • TCI Shanghai:2-氨基-5-硝基二苯甲酮 2-Amino-5-nitrobenzophenone,>;98.0%(LC)(1775-95-7)
  • Alfa Aesar:2-氨基-5-硝基苯并苯酮,98% 2-Amino-5-nitrobenzophenone, 98%(1775-95-7)
  • Acros Organics:2-Amino-5-nitrobenzophenone, 98%(1775-95-7)
  • MOL 文件:1775-95-7.mol
  • 溶于乙醇、乙酸，溶解度：3 MG/L 水 (20 C)，0.21 G/100 ML 甲醇 ，0.21 G/100 ML 乙醇，0.15 G/100 ML 异丙醇 ，17 G/100 ML N,N-DMF，3 G/100 ML 丙酮，1.5 G/100 ML 氯仿。
  • 2-氨基-5-硝基二苯甲酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A1134 2-氨基-5-硝基二苯甲酮 2-Amino-5-nitrobenzophenone 25G 429元 2010/06/21 199220250 2-氨基-5-硝基二苯甲酮 2-Amino-5-nitrobenzophenone 98% 25 GR 461元 2010/06/21 199221000 2-氨基-5-硝基二苯甲酮 2-Amino-5-nitrobenzophenone 98% 100 GR 1180元
  • 方法一:由对硝基苯胺和苯甲酰氯缩合而得。将对硝基苯胺、苯甲酰氯和氯化锌加入反应罐内搅拌，加热使物料全部熔化。升温至140℃，保温30min。继续升温至200℃左右，保温反应2h，冷至115-120℃，搅拌水解15h。加入2.5倍稀盐酸，冷至35℃，过滤。滤饼用稀盐酸洗涤，滤干。加4倍量的水搅成糊状，加碱到pH为11，浸泡2-3h（浸泡过程中要补加碱，加碱到pH为11）。过滤，滤饼用水洗使pH为6-7。滤干，干燥得二苯酮粗品。加适量活性炭和10倍量的乙醇，加热回流4h。趁热过滤。滤液冷却结晶。甩滤，滤饼用冷乙醇洗涤，滤干，干燥即得。收率为25%。
  • 下游产品:硝西泮
  • 上游原料:氯化锌 --> 苯甲酰氯 --> 二苯胺 --> 二苯甲酮 --> N-甲基对硝基苯胺 --> 对氯苯甲酸

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Ketones - Carbonyl Compounds
  6. C13 to C14 - Ketones
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Aromatic Ketones

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