2-Piperidinoethyl 4-Amino-5-Chloro-2-Methoxybenzoate 2-哌啶乙基-4-氨基-5-氯-2-甲氧基苯甲酸酯

CAS 186826-17-5 MFCD86826175

化学结构图

186826-17-5
SMILES: COC1C=C(N)C(Cl)=CC=1C(=O)OCCN1CCCCC1

化学属性

Mol. Weight349.25
Mol. FormulaC15H22Cl2N2O3

别名和识别编码

CAS Number186826-17-5
Chemical Name2-Piperidinoethyl 4-Amino-5-Chloro-2-Methoxybenzoate
Synonym 4-Amino-5-chloro-2-methoxybenzoic Acid 2-(1-Piperidinyl)ethyl Ester Hydrochloride
Chemical Name Translation2-哌啶乙基-4-氨基-5-氯-2-甲氧基苯甲酸酯
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Potent, selective 5-HT4 serotonin receptor agonist. New ester of 4-Amino-5-chloro-2-methoxybenzoic acid as potent agonist and antagonist for 5-HT4 receptors.

相关文献及参考

  • [2]. D Yang, et al. New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem. 1997 Feb 14;40(4):608-21.
  • [3]. M Cachard-Chastel, et al. 5-HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice. Br J Pharmacol. 2007 Apr; 150(7): 883–892.
  • Candura, S., et al.: Br. J. Pharmacol., 118, 1965 (1996),
  • Cohen, M., et al.: J. Pharmacol. Exp. Ther., 254, 350 (1990),
  • Yang, D., et al.: J. Med. Chem., 40, 608 (1997),
  • [1]. Langlois, M., et al. Design of a potent 5-HT4 receptor agonist with nanomolar affinity. Bioorganic & Medicinal Chemistry Letters. 1994. 4(12), 1433–1436.
  • [1]. Langlois, M., et al. Design of a potent 5-HT4 receptor agonist with nanomolar affinity. Bioorganic & Medicinal Chemistry Letters. 1994. 4(12), 1433–1436.
  • [2]. D Yang, et al. New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists f

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)

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