CASPASE-1 INHIBITOR TFA SALT

CAS 210345-00-9 MFCD07780829

化学结构图

210345-00-9
SMILES: COC(=O)C[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC1=CNC2C=CC=CC1=2)NC(=O)OCC1C=CC=CC=1)C(=O)CF.OC(=O)C(F)(F)F

化学属性

Mol. FormulaC37H42FN7O10.C2HF3O2
Mol. Weight877.798

别名和识别编码

Chemical NameCASPASE-1 INHIBITOR TFA SALT
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相关文献及参考

  • [2]. Yang D, et al. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish.Nat Commun. 2018 Aug 3;9(1):3052.
  • [3]. Ferko MA, et al. Effects of metal ions on caspase-1 activation and interleukin-1β release in murine bone marrow-derived macrophages.PLoS One. 2018 Aug 23;13(8):e0199936.
  • [4]. Newman ZL, et al. CA-074Me protection against anthrax lethal toxin.Infect Immun. 2009 Oct;77(10):4327-36.
  • [1]. Kamada S, et al. Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.Cell Death Differ. 1997 Aug;4(6):473-8.
  • [1]. Kamada S, et al. Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.Cell Death Differ. 1997 Aug;4(6):473-8.
  • [2]. Yang D, et al. Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish.Nat Commun. 2018

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Cathepsin  (组织蛋白酶)

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