4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid BMS493

CAS 215030-90-3 MFCD15030903

化学结构图

215030-90-3
SMILES:

化学属性

Mol. FormulaC29H24O2
Mol. Weight404.50

别名和识别编码

Chemical Name4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid
Chemicalbook IDCB22518846
Synonym (E)-4-[2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)naphthalen-2-yl]ethen-1-yl]benzoic acid 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(phenylethynyl)-2-naphthalenyl]ethenyl]-benzoic acid BMS204, 493
MDL NumberMFCD17215944
PubChem Substance ID329773282
Chemical Name TranslationBMS493
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分类

  • {SNA} Apoptosis and Cell Cycle, Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecule Alphabetical Index, Bristol-Myers Squibb, Cell Cycle Proteins, Antibodies and Reagents, Cell Cycle Regulators, Gene Regulation and Expression, PPAR and RXR Regulators, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Yu Z, et al. Apoptosis induced by atRA in MEPM cells is mediated through activation of caspase and RAR. Toxicol Sci. 2006 Feb;89(2):504-9.
  • [1]. Elgamal RM, et al. BMS 493 Modulates Retinoic Acid-Induced Differentiation During Expansion of Human Hematopoietic Progenitor Cells for Islet Regeneration. Stem Cells Dev. 2018 Aug 1;27(15):1062-1075.
  • [1]. Elgamal RM, et al. BMS 493 Modulates Retinoic Acid-Induced Differentiation During Expansion of Human Hematopoietic Progenitor Cells for Islet Regeneration. Stem Cells Dev. 2018 Aug 1;27(15):1062-1075.
  • [2]. Yu Z, et al. Apoptosis induced by atRA in MEPM cells is mediated through activation of caspase and RAR. Toxicol Sci. 2006 Feb;89(2):504-9.

安全信息

WGK Germany2
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. RAR/RXR  (维甲酸受体)

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