9,18-(Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8,9)(1,5,8, 11,14)thiatetraazacyclooctadecino(18,17-b)indole-6-acetic acid,1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-2,14-dihydroxy-21-(2-hydroxy-1-methylpropyl )-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide

CAS 21705-02-2 MFCD01747008

化学结构图

21705-02-2
SMILES: CCC(C)[C@@H]1NC(=O)CNC(=O)[C@@H]2CC3C4C=CC(O)=CC=4NC=3S(=O)C[C@@H](NC(=O)CNC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1CC(O)CC1C(=O)N[C@@H]([C@@H](C)[C@H](C)O)C(=O)N2

化学属性

Mol. FormulaC39H53N9O14S
Mol. Weight904.07

别名和识别编码

Chemical Name9,18-(Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8,9)(1,5,8, 11,14)thiatetraazacyclooctadecino(18,17-b)indole-6-acetic acid,1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-2,14-dihydroxy-21-(2-hydroxy-1-methylpropyl )-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide
Synonym alpha-Amanitin, 1-L-aspartic acid-3-(4-hydroxy-L-isoleucine)-, (S)- epsilon-Amanitin
CAS Number21705-02-2
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安全信息

RTECSNJ8325000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,2142,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRBCAI CRC Critical Reviews in Biochemistry.  (CRC Press, Inc., 2000
   Corporate Blvd., NW, Boca Raton, FL 33431)  V.1-    1972-
   Volume(issue)/page/year: 5,185,1978

系列性分类


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