Olesoxime 奥利索西

CAS 22033-87-0 MFCD00201488

化学结构图

22033-87-0
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4=C/C(/CC[C@]4(C)[C@H]3CC[C@]12C)=N\O

化学属性

Mol. FormulaC27H45NO
Mol. Weight399.65
Melting Point145-148 ºC
Density1.10

别名和识别编码

Chemical NameOlesoxime
Synonym Cholest-4-en-3-one oxime NSC 21311 Olesoxime cholest-4-en-3-one, oxime
CAS Number22033-87-0
Chemical Name Translation奥利索西
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, T, 生物活性小分子, 细胞生物学

相关文献及参考

  • [2]. Bordet T, et al. Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound. Pharmaceuticals (Basel). 2010 Jan 28;3(2):345-368
  • [3]. Bordet T, et al. Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J Pharmacol Exp Ther. 2007 Aug;322(2):709-20.
  • [4]. Xiao WH, et al. Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel. Pain. 2009 Dec 15;147(1-3):202-9
  • [1]. Martin LJ, et al. Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Aug;13(8):568-80.
  • [1]. Martin LJ, et al. Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Aug;13(8):568-80.
  • [2]. Bordet T, et al. Olesoxime (TRO19

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Mitochondrial Metabolism  (线粒体代谢)

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