Aspartame 天冬氨酰苯丙氨酸甲酯
CAS 22839-47-0 MFCD00002724
化学结构图
SMILES: COC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H](N)CC(O)=O
化学属性
| Mol. Formula | HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3 |
|---|---|
| Mol. Weight | 294 |
| Melting Point | 248-250 |
| Density | 1.28 |
别名和识别编码
| Chemical Name | Aspartame |
|---|---|
| CAS Number | 22839-47-0 |
| Synonym | 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, ?-Aspartame ?-L-Aspartyl- Canderel Dipeptide Sweetener E 951 Equal L-?-Aspartyl-L-phenylalanine 2-Methyl Ester L-Aspartame L-Aspartyl-L-phenylalanine methyl ester; Equal; Nutrasweet N-(L-α-天冬氨酰)-L-苯丙氨酸甲酯 天冬甜素 阿斯巴甜 N-(L-α-天冬氨酰)-L-苯丙氨酸甲酯 N-L--Aspartyl-L-phenylalanine 1-Methyl Ester N-L-α-Aspartyl-L-phenylalanine 1-Methyl Ester NutraSweet Palsweet Diet Zero-Cal 天冬甜素 天冬酰-苯丙氨酸甲酯 蛋白糖,甜乐,甜味素,N-L-α-天冬氨酰-L-苯丙氨酸甲酯,天冬氨酰苯丙氨酸甲酯 阿斯巴甜 |
| Beilstein Registry Number | 2223850 |
| PubChem Substance ID | 87562491 |
| EC Number | 245-261-3 |
| MDL Number | MFCD00002724 |
| Reaxys-RN | 2223850 |
| Merck Number | 839 |
| Chemical Name Translation | 天冬氨酰苯丙氨酸甲酯 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- A, AR to AZ, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, E numbers (Food Additives), E900–E999 (miscellaneous), E951, Food & Beverage Standards, Market Segments, Neats and Solutions,
- {SNA} Dipeptides, Di
产品应用
- A dipeptide ester about 160 times sweeter than sucrose in aqueous solution. A non-nutritive sweetener.
相关文献及参考
- Oppermann, et al.: J. Nutr., 103, 1454 (1973),
- Cloninger, B., et al.: Science, 170, 81 (1970),
- Merck:839
安全信息
- S22 Do not breathe dust 不要吸入粉尘；
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
GHS Symbol
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),37,1996
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),37,1996
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),37,1996
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 3710 ug/kg TOXIC EFFECTS : Skin and Appendages - dermatitis, allergic (after systemic exposure) REFERENCE : AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 104,207,1986
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 4 gm/kg SEX/DURATION : female 15-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - behavioral REFERENCE : RCPBDC Research Communications in Psychology, Psychiatry and Behavior. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1976- Volume(issue)/page/year: 9,385,1985
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 449 gm/kg
SEX/DURATION : male 2 week(s) pre-mating
female 2 week(s) pre-mating - 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
alive at weaning per # alive at day 4)
REFERENCE :
NETOD7 Neurobehavioral Toxicology. (Fayetteville, NY) V.1-2, 1979-80. For
publisher information, see NTOTDY. Volume(issue)/page/year: 1,79,1979TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE : 32500 mg/kg SEX/DURATION : female 1-65 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - behavioral REFERENCE : NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 11,413,1989
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 275 gm/kg
SEX/DURATION : male 2 week(s) pre-mating
female 2 week(s) pre-mating - 16 dTYPE OF TEST : TDLo - Lowest p
其他信息
- 微溶于水（约1%）和乙醇（0.26mg/100ml）。无臭、有强烈甜味，其稀溶液的甜度约为蔗糖的100-200倍。其甜味与砂糖十分相似，并有清凉感。0.8%水溶液的pH值为4-6.5。在水溶液中不稳定，易分解而失去甜味，低温时和pH值3-5时较稳定。
京ICP备2020036287号