安全信息
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 260 mg/m3/6H/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0536058
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 395 gm/kg/132W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: ORNL-5762
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 312 gm/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
39,1718,1979
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 156 gm/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerl
RTECS | RN9100000 |
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >5 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury
Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/13/1963
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2140 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury
Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/13/1963
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - coma
Vascular - shock
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: ORNL-5375
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 50 mg/L
REFERENCE :
CIHPDR Zhongguo Yixue Kexueyuan Xuebao. Journal of the Chinese Academy of
Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop.
Rep. China) V.1- 1979- Volume(issue)/page/year: 6,210,1984
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 5700 ug/plate
REFERENCE :
CIHPDR Zhongguo Yixue Kexueyuan Xuebao. Journal of the Chinese Academy of
Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop.
Rep. China) V.1- 1979- Volume(issue)/page/year: 6,210,1984
TYPE OF TEST : Micronucleus test
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 1 gm/kg
REFERENCE :
CIHPDR Zhongguo Yixue Kexueyuan Xuebao. Journal of the Chinese Academy of
Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop.
Rep. China) V.1- 1979- Volume(issue)/page/year: 6,210,1984