(R)-4-((3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)sulfonyl)-N,N-dimethylbenzamide 4-[[3-氯-4-[[(2R)-3,3,3-三氟-2-羟基-2-甲基-1-氧代丙基]氨基]苯基]磺酰基]-N,N-二甲基苯甲酰胺

CAS 252017-04-2 MFCD52017042

化学结构图

252017-04-2
SMILES:

别名和识别编码

Chemical Name(R)-4-((3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)sulfonyl)-N,N-dimethylbenzamide
Chemical Name Translation4-[[3-氯-4-[[(2R)-3,3,3-三氟-2-羟基-2-甲基-1-氧代丙基]氨基]苯基]磺酰基]-N,N-二甲基苯甲酰胺
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相关文献及参考

  • [2]. Mayers RM, et al. AZD7545, a novel inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2), activates pyruvate dehydrogenase in vivo and improves blood glucose control in obese (fa/fa) Zucker rats. Biochem Soc Trans. 2003 Dec;31(Pt 6):1165-7.
  • [3]. Cesi G et al. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells. Mol Cancer. 2017 Jun 8;16(1):102.
  • [1]. Morrell JA, et al. AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2. Biochem Soc Trans. 2003 Dec;31(Pt 6):1168-70.
  • [1]. Morrell JA, et al. AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2. Biochem Soc Trans. 2003 Dec;31(Pt 6):1168-70.
  • [2]. Mayers RM, et al. AZD7545, a novel inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2), activates pyruvate dehydrogenase in vivo and improves blood glucose control in obese (fa/fa) Zucker rats. Biochem Soc Trans. 2003 Dec;31(Pt 6):1165-7.
  • [3]. Ces

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. PDHK  (丙酮酸脱氢酶激酶)

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