2-Propen-1-one,1-(6-(2-(dimethylamino)ethoxy)-4,7-dimethoxy-5-benzofuranyl)- 3-(p-methoxyphenyl)-

CAS 26225-59-2 MFCD00868315

化学结构图

26225-59-2
SMILES: CN(C)CCOC1C(C(=O)/C=C/C2C=CC(=CC=2)OC)=C(OC)C2C=COC=2C=1OC

化学属性

Mol. FormulaC24H27NO6
Mol. Weight425.52

别名和识别编码

Chemical Name2-Propen-1-one,1-(6-(2-(dimethylamino)ethoxy)-4,7-dimethoxy-5-benzofuranyl)- 3-(p-methoxyphenyl)-
Wiswesser Line NotationT56 BOJ FO1 GV1U1R DO1& HO2N1&1 IO1
Synonym 5-(p-Methoxy-cinnamoyl)-4,7-dimethoxy-6-dimethylaminoethoxybenzofuran Mecinarone
CAS Number26225-59-2
Beilstein Registry Number1670082
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安全信息

RTECSUD5574500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 63 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   1,133,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 244 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,782,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   1,133,1976

系列性分类

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