Uridine 5'-(trihydrogen diphosphate), disodium salt 尿苷-5'-二磷酸二钠盐

CAS 27821-45-0 MFCD00149253

化学结构图

27821-45-0
SMILES: O.[Na+].[Na+].[O-]P(O)(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O

化学属性

Mol. FormulaC9H12N2Na2O12P2· xH2O
Mol. Weight448.12 (anhydrous basis)

别名和识别编码

Chemical NameUridine 5'-(trihydrogen diphosphate), disodium salt
Synonym 尿苷-5'-二磷酸 尿苷-5′-二磷酸 二钠盐 水合物 5'-UDP-Na2
MDL NumberMFCD00149253
PubChem Substance ID57653599
Beilstein Registry Number8817400
EC Number248-678-9
CAS Number27821-45-0
Chemical Name Translation尿苷-5'-二磷酸二钠盐
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分类

  • {SNA} Nucleotides, 核苷，核苷酸和寡核苷酸, 生化试剂
  • {SNA} Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides

相关文献及参考

  • [2]. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immunol. 2011 Mar 15;186(6):3701-9.
  • [3]. Edyta Gendaszewska-Darmach, et al. Nucleoside 5'-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation. Oncotarget. 2016 Oct 25;7(43):69358-69370.
  • [4]. Zainab S B Abbas, et al. UDP-sugars activate P2Y 14 receptors to mediate vasoconstriction of the porcine coronary artery. Vascul Pharmacol. 2018 Apr;103-105:36-46.
  • [1]. Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89.
  • [1]. Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89.
  • [2]. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immuno

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleotides - Nucleosides, Nucleotides, Oligonucleotides
  1. Medical Research Areas
  2. GPCR & G Protein
  3. P2Y Receptor  (P2Y受体)
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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