(2S,4R)-4-Methylglutamic acid （2S,4R）- 4 -甲基谷氨酸
CAS 31137-74-3 MFCD00937765
化学结构图
SMILES: C[C@@H](C[C@@H](N)C(O)=O)C(O)=O |&1:1,3|
化学属性
| Mol. Formula | C6H11NO4 |
|---|---|
| Mol. Weight | 161.16 |
别名和识别编码
| Chemical Name | (2S,4R)-4-Methylglutamic acid |
|---|---|
| Synonym | SYM-2081 |
| MDL Number | MFCD00937765 |
| PubChem Substance ID | 24895059 |
| CAS Number | 31137-74-3 |
| Chemical Name Translation | （2S,4R）- 4 -甲基谷氨酸 |
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分类
- {SNA} AMPA/Kainate Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, M, Neuroscience, Neurotransmission, Neurotransmitters
- {SNA} AMPA/Kainate Antagonists, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, 细胞信号转导和神经科学, 细胞生物学
- AMPA/Kainate Antagonists, Bioactive Small Molecules, Cell Biology, Cel
相关文献及参考
- Ta, L.E., et al., SYM-2081 a kainate receptor antagonist reduces allodynia and hyperalgesia in a freeze injury model of neuropathic pain. Brain Res. 858 , 106-120, (2000) 摘要
- Toms, N.J., et al., A novel kainate receptor ligand [ 3 H]-(2S,4R)-4-methylglutamate: pharmacological characterization in rabbit brain membranes. Neuropharmacology 36 , 1483-1438, (1997)
- Zhou, L.M., et al., (2S,4R)-4-methylglutamic acid (SYM 2081): a selective high-affinity ligand for kainate receptors. J. Pharmacol. Exp. Ther. 280 , 422-427, (1997) 摘要
- Jones, K.A., et al., Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate. Neuropharmacology 36 , 853-863, (1997) 摘要
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