N-(3,4-Dichlorophenyl)-N,N-Dimethylurea 敌草隆

CAS 330-54-1 MFCD00018136

化学结构图

330-54-1
SMILES: CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1

化学属性

Mol. FormulaC9H10Cl2N2O
Mol. Weight233.09
Density1.48
Melting Point158-159 °C
TSCAYes
Boiling Point180-190 °C at 760 mmHg
Solubility略溶于水. 0.0042 G/100 ML
Flash Point180-190°C

别名和识别编码

Chemical NameN-(3,4-Dichlorophenyl)-N,N-Dimethylurea
Synonym Diuron {LY} Diuron {} {LY} Diuron {} {} {LY} Diuron {} {} {} {LY} Diuron {} {} {} {} {LY} Diuron {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diuron {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00018136
CAS Number330-54-1
Beilstein Registry Number2215168
PubChem Substance ID3120
EC Number206-354-4
Merck Number3382
Reaxys-RN2215168
Chemical Name Translation敌草隆
Wiswesser Line NotationGR BG DMVN1&1
InChIInChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)
Canonical SMILESO=C(NC1=CC=C(Cl)C(Cl)=C1)N(C)C
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分类

  • {SNA} 2000/60/EC,
  • {SNA} 2000/60/EC, All alphabetically sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Cell Biology, Chromatography, D, DIG-DY, DIO - DIZ, Environmental Standards, European Community: ISO, DIN and DL 152, Method and Regulation Specific, Pesticides & Metabolites, Pesticides, Bactericides, Fungicides and Disinfectants,
  • {SNA} Bioactive Small Molecules, Building Blocks, Carbonyl Compounds, Chemical Synthesis, DIG-DY, Organic Building Blocks, Ureas, 细胞生物学
  • {SNA} Building Blocks,

产品应用

  • 该品为除草剂,用于防除非耕地一般杂草,也用于棉田选择性除草。

相关文献及参考

  • Merck: 14,3382
  • Short: EINECS
  • Short: IV/8A

安全信息

GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
  • P304+
  • P305+P351+P338
  • P308+P313
  • P332+P313
  • P337+P313
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H302+H312+H332
  • H302 Harmful if swallowed 吞食有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H332 Harmful if inhaled 吸入有害
  • H312 Harmful in contact with skin 皮肤接触有害
WGK Germany3
Signal word Danger Warning
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSYS8925000
Safety Statements
  • S13 Keep away from food, drink and animal foodstuffs 远离食品、饮料和动物饲料保存;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S2 Keep out of the reach of children 避免儿童触及;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Packing GroupIII
UN Number 2767 3077 UN 3077 9/PG 3 UN3077
Risk Statements
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R22 Harmful if swallowed 吞咽有害
  • R36 Irritating to eyes 刺激眼睛
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R48/22
  • R50/53
Hazard Codes 9
Storage condition 2-8°C {LY} 2-8°C APPROX 4°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Class9
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 153 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TO

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1017 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - ataxia
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C115,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C115,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 3 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,353,1978

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,353,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1250 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   BECTA6 Bulletin of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   07094)  V.1-    1966-  Volume(issue)/page/year: 22,522,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 360 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(8),83,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1935 mg/kg
SEX/DURATION            : female 6-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-160

其他信息

  • 毒害物质数据:330-54-1(Hazardous Substances Data)
  • NIST化学物质信息:Urea, 3-(3,4-dichlorophenyl)-1,1-dimethyl-(330-54-1)
  • 敌草隆价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D1328 3-(3,4-二氯苯基)-1,1-二甲基脲 3-(3,4-Dichlorophenyl)-1,1-dimethylurea 500G 1150元 2014/06/02 D1328 3-(3,4-二氯苯基)-1,1-二甲基脲 3-(3,4-Dichlorophenyl)-1,1-dimethylurea 25G 135元 2010/05/25 L02986 3-(3,4-二氯苯基)-1,1-二甲基脲, 97% 3-(3,4-Dichlorophenyl)-1,1-dimethylurea, 97% 50g 465元
  • 稳定性:Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
  • 毒性:大鼠急性经口LD 50 3400mg/kg。高浓度时对眼睛和黏膜有刺激性。慢性毒性试验大鼠无作用剂量为250mg/kg(2年),狗无作用剂量为125mg/kg(1年)。
  • 在180℃时分解。在烃类溶剂中溶解度极低,25℃水中溶解42ppm,不溶于大多数有机溶剂。遇强酸、强碱可被分解。
  • 取代脲类除草剂:敌草隆与灭草隆、利谷隆是三种常用的取代脲类除草剂,敌草隆属内吸传导型除草剂,具有一定的触杀活力,可被植物的根和叶吸收,以根系吸收为主,杂草根系吸收药剂后,传到地上叶片中,并沿着叶脉向周围传播,抑制光合作用的希尔反应,致使叶片失绿,叶尖和叶缘褪色,进而发黄枯死。敌草隆在低剂量情况下,可作为选择性除草剂使用,高剂量下则可作为灭生性除草剂。敌草隆适于水稻、棉花、玉米、甘蔗及果、胶、桑、茶园使用,防除稗草、马唐、狗尾草、蓼、藜及眼子菜等。对人、畜低毒,大鼠急性口服LD50为3400mg/kg,高浓度时对眼和黏膜有刺激作用。敌草隆对种子萌发及根系无显著影响,药效期可维持60天以上。 1,敌草隆对麦苗有杀伤作用,麦田禁用。在茶、桑、果园宜采用毒土法,以免发生药害。 2,敌草隆对棉叶有很强的触杀作用,施药必须施于土表,棉苗出土后不宜使用敌草隆。 3,砂性土壤,用药量应比粘质土壤适当减少。砂性漏水稻田不宜用。 4,敌草隆对果树及多种作物的叶片有较强的杀伤力,应避免药液飘移到作物叶片上。桃树对敌草隆敏感,使用时应注意。 5,喷过敌草隆的器械必须用清水反复清洗。 6,单独使用时,敌草隆不易被大多数植物叶面吸收,需加入一定的表面活性剂,提高植物叶面的吸收能力。
  • 用途:取代脲类除草剂,具有内吸传导作用和一定触杀作用。药剂被植物根系或叶片吸收后抑制光合作用,致使叶片失绿,叶尖和边缘褪色,导致植株因缺乏营养而死亡。敌草隆在低剂量下可通过位差及时差选择进行除草。高剂量时成为灭生性除草剂。主要用于棉花、大豆、番茄、烟草、草莓、葡萄、果园、橡胶园等作物防除一年生禾本科杂草和某些阔叶杂草,如旱稗、马唐、狗尾草、野苋草、莎草、藜等。如在棉田播后出苗前,用25%敌草隆可湿性粉剂30~45g/100m 2 ,对水7.5kg,均匀喷雾土表,防效90%以上;用于水稻田防除眼子菜用7.5~15g/100m 2 ,防效90%以上;果树、茶园在杂草萌芽高峰期,用25%可湿性粉剂30~37.5g/100m 2 ,对水5.3kg喷雾土表,亦可在中耕除草后进行土壤喷雾处理。
  • RTECS号:YS8925000
  • 外观性质:纯品为白色无臭晶体。
  • HazardClass:9
  • 生产方法:由3,4-二氯苯胺、光气和二甲胺为原料合成。
  • 图谱信息:敌草隆(330-54-1)核磁图( 1 HNMR) 敌草隆(330-54-1)核磁图( 13 CNMR) 敌草隆(330-54-1)红外图谱(IR2) 敌草隆(330-54-1)质谱(MS)
  • PackingGroup:III
  • MOL 文件:330-54-1.mol

系列性分类


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