Sodium 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate 1-乙基-7-甲基-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸钠盐

CAS 3374-05-8 MFCD00064376

化学结构图

3374-05-8
SMILES: CCn1cc(C(=O)[O-])c(=O)c2ccc(C)nc21.[Na+]

化学属性

Mol. FormulaC12
Mol. Weight254
TSCANo
Melting Point>280°
Appearance powder
SolubilityH2O: 50 mg/mL, clear, faintly yellow

别名和识别编码

Chemical NameSodium 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate
MDL NumberMFCD00064376
CAS Number3374-05-8
Synonym 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 1,4-Dihydro-1-ethyl-4-oxo-7-methyl-1,8-naphthyridine-3-carboxylic acid sodium salt NALIDIXIC ACID SODIUM GAMMA-IRRADIATED*M OLECULAR BI 1-ETHYL-1,4-DIHYDRO-7-METHYL-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID SODIUM SALT sodiumnilixalate 萘啶酮酸钠 nalidixatesodium sodium 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate NALIDIXIC ACID SODIUM SALT MOLEC 8-naphthyridine-3-carboxylicacid,1-ethyl-1,4-dihydro-7-methyl-4-oxo-sodiu 1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸钠盐 sodiumnalidixate Sodium 1 - ethyl - 1,4 - dihydro - 7 - methyl - 4 - oxo - 1,8 - Sodium 1 - nalidixic acid sodium gamma-irradiated*molecular NALIDIXIC ACID SODIUM SALT Sodium 1 - ethyl - 1,4 -
PubChem Substance ID3864541
Beilstein Registry Number3580062
EC Number222-159-7
Chemical Name Translation1-乙基-7-甲基-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸钠盐
LabNetwork Molecule IDLN00195069
InChIInChI=1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
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分类

  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Biochemicals and Reagents, Chemical Structure Class, Genetic Marker Selection, Inhibits an Enzyme, Interferes with DNA Synthesis, L - Z, Mechanism of Action, Quinolones and Fluoroquinolones, Spectrum of Activity
  • {SNA} Antibacterial, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Apoptosis and Cell Cycle, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Chemical Structure Class, DNA Repair Regulators, DNA metabolism,
  • {SNA} Antibacterial,

安全信息

RTECSQN2885500
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Symbol
Precautionary statements
  • P342+P311
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
WGK Germany3
Signal word
Hazard Codes Xn
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S24 Avoid contact with skin 避免皮肤接触；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S34 None 避免冲击和摩擦；
Risk Statements
  • R42/43
Storage condition 2-8°C 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Cells - not otherwise specified
DOSE/DURATION           : 900 mg/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   60,287,1987

其他信息

  • MOL 文件:3374-05-8.mol
  • Sigma Aldrich:3374-05-8(sigmaaldrich)
  • F:8-10

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. N - Bioactive Small Molecules

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