Benz(a)acridine, 8,12-dimethyl-

CAS 3518-05-6 MFCD03518056

化学结构图

3518-05-6
SMILES: Cc1cccc2c(C)c3c(ccc4ccccc43)nc12

化学属性

Mol. FormulaC19H15N
Mol. Weight257.35

别名和识别编码

Chemical NameBenz(a)acridine, 8,12-dimethyl-
Chemicalbook IDCB72135789
Wiswesser Line NotationT D6 B666 JNJ C1 H1
Synonym 8,12-Dimethylbenz(a)acridine 1,10-Dimethyl-5,6-benzacridine
CAS Number3518-05-6
Beilstein Registry Number0190112
InChIKeyARUPRRXZUJYLKR-UHFFFAOYSA-N
PubChem Substance ID197792
InChIInChI=1S/C19H15N/c1-12-6-5-9-15-13(2)18-16-8-4-3-7-14(16)10-11-17(18)20-19(12)15/h3-11H,1-2H3
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Lungs, Thorax, or Respiration - bronchiolar constriction
REFERENCE :
   ACRSAJ Advances in Cancer Research.  (Academic Press, Inc., 465 S. Lincoln
   Dr., Troy, MO 63379) V.1-    1953-  Volume(issue)/page/year: 4,315,1956

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg/10D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   BAFEAG Bulletin de l'Association Francaise pour l'Etude du Cancer.  (Paris,
   France)  V.1-52, 1908-65. For publisher information, see BUCABS.
   Volume(issue)/page/year: 34,22,1947

RTECSCU3510000

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