10,11-Dihydro-5H-Dibenzo[B,F]Azepine-5-Carboxamide 10,11-二氢酰胺咪嗪

CAS 3564-73-6 MFCD00005072

化学结构图

3564-73-6
SMILES: NC(=O)N1c2ccccc2CCc2ccccc21

化学属性

Mol. FormulaC15H14N2O
Mol. Weight238.28
Melting Point205-210 °C
TSCANo
Boiling Point394.5±52.0 °C at 760 mmHg

别名和识别编码

Chemical Name10,11-Dihydro-5H-Dibenzo[B,F]Azepine-5-Carboxamide
CAS Number3564-73-6
Synonym 10,11-Dihydrocarbamazepine 10,11-dihydrocarbamazepine dihydrocarbamazepine {} {LY} 10,11-Dihydrocarbamazepine {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 10,11-Dihydrocarbamazepi
MDL NumberMFCD00005072
EC Number222-649-0
Beilstein Registry Number0196969
PubChem Substance ID19099
Chemical Name Translation10,11-二氢酰胺咪嗪
Wiswesser Line NotationT C676 BN&T&J BVZ
LabNetwork Molecule IDLN00225215
InChIInChI=1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18)
Canonical SMILESO=C(N1C2=CC=CC=C2CCC3=CC=CC=C31)N
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分类

  • Pharmaceuticals
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Other Heterocyclic Building Blocks
  • Impurities
  • Heterocycles
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Others
  • Intermediates & Fine Chemicals
  • Amines

产品应用

  • A dihydro impurity of Carbamazepine (C175840)

相关文献及参考

  • Bhoir, I., et al.: Indian Drugs, 36, 231

安全信息

RTECSHN8300000
WGK Germany3
Hazard Codes Xn
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S22 Do not breathe dust 不要吸入粉尘;
GHS Symbol
Precautionary statements
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P340
  • P304+P341
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P333+P313
  • P333+P317
  • P342+P311
  • P342+P316
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P403 Store in a well-ventilated place. 储存在通风良好的地方。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
Signal word Danger
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R42/43
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,88,1964

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

系列性分类


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