Cinacalcet Hydrochloride 盐酸西那卡塞
CAS 364782-34-3 MFCD08067750
化学结构图
SMILES: Cl.C[C@@H](NCCCC1C=C(C=CC=1)C(F)(F)F)C1C=CC=C2C=CC=CC2=1
化学属性
| Mol. Formula | C22H23ClF3N |
|---|---|
| Mol. Weight | 394 |
| Melting Point | 176-178 |
别名和识别编码
| Chemical Name | Cinacalcet Hydrochloride |
|---|---|
| CAS Number | 364782-34-3 |
| Alfabeta Name | NAPHTHALENYLETHYLTRIFLUOROMETHYLPHENYLPROPANAMINEHYDROCHLORIDE RN11331((((()))))----------- |
| MDL Number | MFCD08067750 |
| Synonym | (αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; ®-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine Hydrochloride |
| Chemical Name Translation | 盐酸西那卡塞 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Chiral Reagents
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- The (R) enantiomer of Cinacalcet. Used in clinical trial in secondary hyperparathyroidism.
相关文献及参考
- [2]. D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.
- Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),
- Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003),
- [1]. Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76.
- [1]. Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76.
- [2]. D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312
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