2-Amino-4-bromophenol 2-氨基-4-溴苯酚

CAS 40925-68-6 MFCD00235171

化学结构图

40925-68-6
SMILES: Nc1cc(Br)ccc1O

化学属性

Mol. FormulaC6H6BrNO
Mol. Weight188
Melting Point130-135
Density1.422
TSCANo

别名和识别编码

Chemical Name2-Amino-4-bromophenol
CAS Number40925-68-6
Alfabeta NameAMINOBROMOPHENOL 24---
MDL NumberMFCD00235171
Synonym 4-Bromo-2-aminophenol 5-Bromo-2-hydroxyaniline NSC 523846
Beilstein Registry Number3236448
EC Number250-023-7
Reaxys-RN3236448
PubChem Substance ID87561528
Chemical Name Translation2-氨基-4-溴苯酚
LabNetwork Molecule IDLN00009233
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分类

  • {SNA} Amines, Building Blocks, C6, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Oxygen Compounds, Polyols
  • {SA} Building Blocks, C6 to C8, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds,

相关文献及参考

  • 1. Berezin, A. A.; Koutentis, P. A. , Suzuki-Miyaura reactions of the soluble guanylate cyclase inhibitor NS2028: a non-product specific route to C-8 substituted analogues Tetrahedron 67 , 4069-4078, (2011)
  • 2. Guo, S.; et al., Copper-Catalyzed Oxidative Amination of Benzoxazoles via C-H and C-N Bond Activation: A New Strategy for Using Tertiary Amines as Nitrogen Group Sources Org. Lett. 13 , 522-252, (2011)
  • 3. Tong, Y.; et al., ynthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors Chin. Chem. Lett. 21 , 1415-1418, (2010)
  • 4. Deng, L.; et al., Coordination Chemistry Based Approach to Lipophilic Inhibitors of 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase J. Med. Chem. 52 , 6539-6542, (2009)
  • 5. Lai, C.; et al., Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase Bioorg. Med. Chem. Lett. 16 , 1807, (2006)

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P342+P311
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Danger
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42/43
Hazard Codes Xn
Storage condition 储存温度2-8℃

系列性分类


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