Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root 人参皂苷Rb1

CAS 41753-43-9 MFCD00133367

化学结构图

41753-43-9
SMILES: CC1(C)[C@@H]2CC[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@](C)(CCC=C(C)C)O[C@@H]3OC(CO[C@@H]4OC(CO)[C@@H](O)[C@H](O)C4O)[C@@H](O)[C@H](O)C3O)[C@@]2(C)CC[C@@H]1O[C@@H]1OC(CO)[C@@H](O)[C@H](O)C1O[C@@H]1OC(CO)[C@@H](O)[C@H](O)C1O |&1:3,6,8,10,12,13,16,18,27,32,37,39,43,45,49,53,55,60,62,66,71,73|

化学属性

Mol. FormulaC54H92O23
Mol. Weight1109
Melting Point195-197

别名和识别编码

Chemical NameGinsenoside-Rb1 from Panax ginseng (Korean ginseng) root
Synonym 2-O-β-Glucopyranosyl-(3β,12β)-20-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside Arasaponin E1 Ginsenoside RB1 Gynosaponin C Gypenoside III Panax saponin E Pseudoginsenoside D Sanchinoside E1 人参皂苷 Rb1
MDL NumberMFCD00133367
CAS Number41753-43-9
EC Number255-532-8
PubChem Substance ID24895025
Chemical Name Translation人参皂苷Rb1
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分类

  • {SA} Cell Culture, Nutrition Research, Other adjuvants, Panax ginseng, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), Saponins, Terpenes and Terpenoids (Isoprenoids), Vaccine Adjuvants, Vaccine Production
  • {SNA} Alphabetic, Analytical Standards,
  • Alphabetical, Analytical Standards, Analytical/Chromatography,
  • {SNA} Other adjuvants, Panax ginseng, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), Saponins, Terpenes and Terpenoids (Isoprenoids), Vaccine Adjuvants, 疫苗生产, 细胞培养, 细胞生物学, 营养研究

相关文献及参考

安全信息

RTECSLZ 5856000
GHS Symbol
Precautionary statements
  • P301+P310
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word Danger
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H370 Causes damage to organs 导致器官损伤
  • H331 Toxic if inhaled 吸入中毒
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
  • H311 Toxic in contact with skin 皮肤接触中毒
WGK Germany3
Hazard Codes F,T Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 243 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SYHJAM Saengyak Hakhoechi.  Journal of the Society of Pharmacognosy. (Hanguk
   Saengyak Hakhoe, c/o Natural Products Institute, Seoul National Univ., 28
   Yunkeon-Dong, Chong-ro-ku, Seoul 110, Korea)  1970- Volume(issue)/page/year:
   10,61,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,343,1975

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 50 mg/kg
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 24,2400,1976

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Phytopharma Standards - Life Sciences Standards
  6. Phytopharma Primary Standards - Phytopharma Standards
  1. Life Science 生命科学
  2. Cell Culture 细胞培养
  3. Vaccine Production - Cell Culture
  4. Vaccine Adjuvants - Vaccine Production
  5. Other adjuvants - Vaccine Adjuvants

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