8-CHLORO-CAMP

CAS 41941-56-4 MFCD00153938

化学结构图

41941-56-4
SMILES: NC1=NC=NC2=C1N=C(Cl)N2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O

化学属性

Mol. FormulaC10H11ClN5O6P
Mol. Weight363.65

别名和识别编码

Chemical Name8-Chloroadenosine 3',5'-cyclic-monophosphate
Synonym 8-Chloro-cAMP 8-Chloro-cAMP 8-Chloroadenosine 3′,5′-monophosphate 8-Cl-cAMP 8-Chloro-cAMP 8-Chloroadenosine 3',5'-monophosphate 8-Cl-cAMP 8-Chloroadenosine 3′,5′-monophosphate 8-Chloroadenosine 3',5'-monophosphate 8-Cl-cAMP
MDL NumberMFCD00153938
PubChem Substance ID24892338
CAS Number41941-56-4
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分类

  • Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase A (PKA), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology
  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase A (PKA), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Sm

相关文献及参考

  • Juranic, et al., The mechanism of 8-Cl-cAMP action. J. Exp. Clin. Cancer Res 17 , 269-275, (1998) 摘要
  • Propper, et al., Phase I study of the novel cyclic AMP (cAMP) analogue 8-chloro-cAMP in patients with cancer: toxicity, hormonal, and immunological effects. Clin. Cancer Res. 5 , 1682-1689, (1999) 摘要
  • Halgren, et al., 8-Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8-Cl-adenosine. Blood 92 , 2893, (1998) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Cyclic Nucleotides and Analogs - Cyclic Nucleotide Metabolism
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Cyclic Nucleotides and Analogs - Cyclic Nucleotide Metabolism

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