RP107

CAS 496864-15-4 MFCD04973541

化学结构图

496864-15-4
SMILES: CCCCC1=C(NC2N=CC=NC=21)C1C=CC(=CC=1)OC

化学属性

Mol. FormulaC16H17N3O
Mol. Weight267.33

别名和识别编码

Chemical NameRP-107
Synonym 7-n-Butyl-6-(4-hydroxyphenyl)[5H]-pyrrolo[2,3-b]pyrazine
MDL NumberMFCD04973541
CAS Number496864-15-4
PubChem Substance ID329824024
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chloride Channel Modulators, Ion Channels, Monovalent Ion Channels, R, Voltage-gated Ion Channels
  • {SNA} Bioactive Small Molecule Alphabetical Index, Chloride Channel Modulators, Ion Channels, Monovalent Ion Channels, R, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chloride Channel Modulators, Ion Channels, Monovalent Ion Channels, R, Voltage-gated Ion Channels

相关文献及参考

  • Noel, S., et al., Discovery of pyrrolo[2,3-b]pyrazines derivatives as submicromolar affinity activators of wild type, G551D, and F508del cystic fibrosis transmembrane conductance regulator chloride channels. J. Pharmacol. 319 , 349-359, (2006)

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Chloride Channel Modulators - Monovalent Ion Channels

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