Azetidine 杂氮环丁烷

CAS 503-29-7 MFCD00005165

化学结构图

503-29-7
SMILES: C1CNC1

化学属性

Mol. FormulaC3
Mol. Weight57
Density0.847 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.432(lit.)
Boiling Point62°C(lit.)
Flash Point-21°C(lit.)
SolubilityMISCIBLE
TSCAT
Stability对空气和水分敏感

别名和识别编码

Chemical NameAzetidine
CAS Number503-29-7
Alfabeta NameAZETIDINE
MDL NumberMFCD00005165
Synonym Azetidine (Trimethyleneimine) AZETIDINE 四氫吖唉 1,3-Propylenimine 三亞甲亞胺 氮杂环丁二烯 杂氮环丁烷 azetidine Azete, tetrahydro- 氮杂环丁烷
EC Number207-963-8
Beilstein Registry Number102384
PubChem Substance ID10422
Chemical Name Translation杂氮环丁烷
LabNetwork Molecule IDLN00226076
Reaxys-RN102384
InChIInChI=1S/C3H7N/c1-2-4-3-1/h4H,1-3H2
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 4ring; 1fragment
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Others
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Other Heterocyclic Building Blocks

产品应用

  • Employed in a high yielding palladium-catalyzed cross-coupling with aryl bromides. Also used in a Ullmann type coupling with iodonitroflourenes.

相关文献及参考

  • Short: II/19b Title: Molecular Constants: Rotational, Centrifugal Distortion and Related Constants of Diamagnetic Asymmetric Top Molecules Author: Demaison, J.; Hüttner, W.; Vogt, J.; Wlodarczak, G. Editor: Hüttner, W. Source: Landolt-Börnstein, New Series Volume: II/19b Year: 1992 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-54578-6 ISBN: 978-3-540-54578-1 Internet Resource: DOI:10.1007/b44334 RefComment: XI, 488 pages. Abstract: Volume II/19 Molecular Constants mostly from Microwave, Molecular Beam and Sub-Doppler Laser Spectroscopy is a supplement to the earlier volumes II/4, II/6, and II/14. The slight change in the title reflects current trends in the applications of spectroscopic methods. Together, the four volumes collect all the critically evaluated data published up to 1989/90 on constants of free molecules obtained by classical and modern spectroscopy. Volume II/19 is divided into four parts to record the growing number of investigations, especially in the microwave and millimeter wave regions, where modern techniques like Fourier Transform Microwave Spectroscopy have made new objects of interest such as molecular complexes and clusters accessible to study. Subvolume II/19b contains corresponding data on diamagnetic asymmetric top molecules.
  • Short: II/19c Title: Molecular Constants: Dipole Moments, Quadrupole Coupling Constants, Hindered Rotation and Magnetic Constants of Diamagnetic Molecules Author: Demaison, J.; Hüttner, W.; Tiemann, E.; Vogt, J.; Wlodarczak, G. Editor: Hüttner, W. Source: Landolt-Börnstein, New Series Volume: II/19c Year: 1992 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-54893-9 ISBN: 978-3-540-54893-5 Internet Resource: DOI:10.1007/b44435 RefComment: 8 figs., XI, 295 pages. Abstract: Volume II/19 Molecular Constants mostly from Microwave, Molecular Beam and Sub-Doppler Laser Spectroscopy is a supplem

安全信息

Warnings KEEP COLD, FLAMMABLE, CORROSIVE
Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R11 Highly flammable 非常易燃
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P303+P361+P353+P310+P363
  • P403+P235
  • P301+P330+P331+P310
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P370+P378
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P405 Store locked up. 上锁保管。
  • P304+P340+P310
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Hazard Codes F,C
UN Number 2733
Packing GroupII
Storage condition 2-8°C Air & Moisture Sensitive 储存温度 2-8°C 0-10°C
Hazard Class3/8

其他信息

  • Acros Organics:氮杂环丁烷 Azetidine, 98%(503-29-7)
  • 存储注意事项:空气敏感;氮气保护;湿度敏感
  • MSDS 信息:Trimethylene imine(503-29-7).msds
  • 敏感性:Moisture Sensitive/Air Sensitive
  • 杂氮环丁烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 296730010 杂氮环丁烷 Azetidine 98% 1 GR 4114元 2010/06/21 296732500 杂氮环丁烷 Azetidine 98% 250 MG 1481元
  • 海关编码:29339990
  • 上游原料:氢氧化钠 --> 盐酸 --> 甲醇 --> 乙醚 --> 硫酸 --> 二氯甲烷 --> 石油醚 --> 碳酸钾 --> 氢氧化钾 --> 氯化钠 --> 钯 --> 氢 --> 正丁醇 --> 环氧氯丙烷 --> 1,2-苯二胺 --> 甲基磺酰氯 --> 丙二腈 --> 溴化苄 --> 甲基叔丁基醚 --> 乙二醇二甲醚 --> 1-溴-3-氯丙烷 --> 10%钯碳 --> 二苯甲胺 --> 1-溴-3-甲基-2-丁烯 --> 三甲基乙酸甲酯 --> 3-氨基-1-丙醇
  • 检测方法:GC,NMR,MS
  • Sigma Aldrich:503-29-7(sigmaaldrich)
  • F:2-10
  • MOL 文件:503-29-7.mol
  • 下游产品:氨曲南

系列性分类


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