• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Benzimidazoles, Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks
• {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 1fragment
• {Chemicalbook} 农药中间体: 杀菌剂中间体: 三唑类杀菌剂

产品应用

• 测定钴的试剂。有机合成中间体。

相关文献及参考

• Short: II/24C
• Merck: 14,1081 Beilstein:23,131
• Merck: 14,1081
• Short: II/24B

安全信息

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,22,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2910 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 105,486,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 445 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 14,130,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 385 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 95,123,1953

TYPE OF

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   CHIMAD Chimia.  (Postfach 2027, CH-4001 Basel, Switzerland)  V.1-    1947-
   Volume(issue)/page/year: 27,68,1973

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 mg/disc
REFERENCE :
   APMBAY Applied Microbiology.  (Washington, DC)  V.1-30, 1953-75.  For
   publisher information, see AEMIDF.  Volume(issue)/page/year: 6,23,1958

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 15 mmol/L/48H
REFERENCE :
   ANBCA2 Analytical Biochemistry.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1960-  Volume(issue)/page/year: 75,45,1976

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 gm/L
REFERENCE :
   ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie.  (Akademie-Verlag GmbH,
   Postfach 1233, Berlin DDR-1086 Ger. Dem. Rep.)  V.1-    1960-
   Volume(issue)/page/year: 12,583,1972

其他信息

• 毒性分级:中毒
• Alfa Aesar:苯并咪唑,99% Benzimidazole, 99%(51-17-2)
• Hazard Note:Irritant
• 急性毒性:口服-大鼠 LD50: 500 毫克/公斤; 口服-小鼠 LD50: 2910 毫克/公斤
• 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
• Sigma Aldrich:51-17-2(sigmaaldrich)
• 方法一:其制备方法是将粉碎好的邻苯二胺加入反应釜内，然后抽入甲酸，保持反应温度95～98℃搅拌2h，冷却析出结晶，再用10％NaOH中和至微碱性，冷却过滤，用水洗涤、干燥即得苯并咪唑。
• 图谱信息:苯并咪唑(51-17-2)核磁图( 1 HNMR) 苯并咪唑(51-17-2)红外图谱(IR2) 苯并咪唑(51-17-2)红外图谱(IR1) 苯并咪唑(51-17-2)质谱(MS) 苯并咪唑(51-17-2)核磁图( 13 CNMR)
• MOL 文件:51-17-2.mol
• 呈弱碱性，微溶于冷水和乙醛，稍溶于热水，易溶于乙醇、沸二甲苯；酸及强碱水溶液，几乎不溶于苯和石油醚。有较好的化学稳定性。
• TCI Shanghai:1-苯并咪唑 Benzimidazole,>;98.0%(T)(51-17-2)
• 海关编码:29339990
• 用途一:用于合成维生素B12等药物和制备高分子化合物等
• 苯并咪唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30018524 苯并咪唑;苯并二唑 25g 49元 2011/04/16 B0054 苯并咪唑 Benzimidazole 25G 274元 2011/04/16 B0054 苯并咪唑 Benzimidazole 500G 1630元
• Acros Organics:苯并咪唑 Benzimidazole, 98%(51-17-2)
• 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物烟雾
• 类别:农药
• 方法二:由邻苯二胺与甲酸经环合而得。将邻苯二胺与甲酸的混合物在水浴上加热2h，冷却，用10%氢氧化钠溶液调节pH至10，将析出的固体滤出，用冷水洗涤得粗品。粗品加水微沸，加活性炭脱色，趁热过滤，滤液冷至室温，过滤，冷水洗涤，在100℃干燥得成品。粗品收率90%。
• 储运特性:通风低温干燥
• 上游原料:1,2-苯二胺
• 检测方法:HPLC,NMR
• 用途四:测定钴的试剂。有机合成中间体。
• 用途三:有机合成中间体。测定钴的试剂。
• MSDS 信息:Benzimidazole(51-17-2).msds
• 用途二:苯并咪唑可用于制备杀菌剂抑霉唑、咪鲜胺等的中间体咪唑。
• 下游产品:咪唑 --> 噻苯咪唑 --> 多潘立酮 --> 咪唑-4,5-二羧酸 --> 奥沙米特 --> 奥美拉唑 --> 颜料红 175 --> 2-[[3-[[(2,3-二氢-2-氧代-1H-苯并咪唑-5-基)氨基]甲酰]-2-羟基-1-萘]偶氮]苯甲酸丁酯 --> 2-乙酰基苯并咪唑