KX1-004 5-氟-N-(3-羟基苄基)-1H-吲哚-2-甲酰胺

CAS 518058-84-9 MFCD18058849

化学结构图

518058-84-9
SMILES: O=C(NCc1cccc(O)c1)c1cc2cc(F)ccc2[nH]1

化学属性

Mol. Weight284.29
Appearance white solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical Name Translation5-氟-N-(3-羟基苄基)-1H-吲哚-2-甲酰胺
Chemical NameKX1-004
FormulaC16H13FN2O2
Synonym KX1004; KX 1004; KX1-004.
IUPAC Name5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide.
InChIKeyTUIHIKXCMCXXJG-UHFFFAOYSA-N
InChIInChI=1S/C16H13FN2O2/c17-12-4-5-14-11(7-12)8-15(19-14)16(21)18-9-10-2-1-3-13(20)6-10/h1-8,19-20H,9H2,(H,18,21)
Canonical SMILESO=C(C(N1)=CC2=C1C=CC(F)=C2)NCC3=CC=CC(O)=C3
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产品应用

  • KX1-004 is an Src-protein tyrosine kinase inhibitor to reduce cisplatin ototoxicity while preserving its antitumor effect. KX1-004 has been used to protect the cochlea from hazardous noise.

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Medical Research Areas
  2. Angiogenesis
  3. Src

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