N3-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine N3-(4-氟苯基)-1H-吡唑并[3,4-d]嘧啶-3,4-二胺

CAS 522629-08-9 MFCD03861062

化学结构图

522629-08-9
SMILES: NC1N=CN=C2NN=C(NC3C=CC(F)=CC=3)C2=1

化学属性

Mol. FormulaC11H9FN6
Mol. Weight244.23

别名和识别编码

Chemical NameN3-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
Synonym CGP57380 CGP57380 N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine
MDL NumberMFCD03861062
PubChem Substance ID24724432
CAS Number522629-08-9
Chemical Name TranslationN3-(4-氟苯基)-1H-吡唑并[3,4-d]嘧啶-3,4-二胺
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分类

  • {SNA} Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Mitogen-Activated Protein Kinase (MAPK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Kinase/Phosphatase Biology, Mitogen-Activated Protein Kinase (MAPK),

相关文献及参考

  • Schumann M, and Dobbelstein M., Adenovirus-induced extracellular signal-regulated kinase phosphorylation during the late phase of infection enhances viral protein levels and virus progeny Cancer Res. 66 , 1282-1288, (2006) 摘要
  • Knauf, U., et al., Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2 Mol. Cell. Biol. 21 , 5500-5511, (2001) 摘要
  • Fukunaga, R., and Hunter T., MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates EMBO J. 16 , 1921-1933, (1997) 摘要

安全信息

GHS Symbol
Precautionary statements
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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