(±)-Cloprostenol Sodium Salt Standard 氯前列烯醇钠

CAS 55028-72-3 MFCD55028723

化学结构图

55028-72-3
SMILES: [Na+].[O-]C(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2C=C(Cl)C=CC=2)[C@H](O)C[C@@H]1O |&1:10,11,14,25,28|

化学属性

Mol. Weight446.90 (anhydrous basis)
Melting Point68-70 °C
Mol. FormulaC22H28ClNaO6· xH2O

别名和识别编码

Synonym (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate
PubChem Substance ID24724446
CAS Number55028-72-3
EC Number259-439-3
Chemical Name(±)-Cloprostenol Sodium Salt Standard
Chemical Name Translation氯前列烯醇钠
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分类

  • Arachidonic Acid Cascade, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Prostaglandins
  • {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, CI-CZ, Lipids in Cell Signaling, Prostaglandins, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84.
  • Merck 14 ,2399
  • [1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72.
  • [1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72.
  • [2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84.

安全信息

GHS Symbol
Precautionary statements
  • P305+P351+P338
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word Warning
Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes T
Risk Statements
  • R60 May impair fertility 可能降低生殖能力
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Lipids in Cell Signaling - Cell Signaling and Neuroscience
  5. Arachidonic Acid Cascade - Lipids in Cell Signaling
  6. Prostaglandins - Arachidonic Acid Cascade
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Prostaglandin Receptor  (前列腺素受体)

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