5-Ethyl-5-phenylpyrrolidinone

CAS 5556-57-0 MFCD05556570

化学结构图

5556-57-0
SMILES: CCC1(c2ccccc2)CCC(=O)N1

化学属性

Mol. FormulaC12H15NO
Mol. Weight189.28

别名和识别编码

Wiswesser Line NotationT5MVTJ E2 ER
Chemical Name2-Pyrrolidinone, 5-ethyl-5-phenyl-, (+-)-
Synonym (+-)-5-Ethyl-5-phenyl-2-pyrrolidinone (+-)-5-Ethyl-5-phenylpyrrolid-2-one 5-ethyl-5-phenylpyrrolidinone 5-ethyl-5-phenylpyrrolidinone, (+-)-isomer 5-ethyl-5-phenylpyrrolidinone, (-)-isomer
CAS Number5556-57-0
Beilstein Registry Number1451635
InChIKeyJTSAWYFWKYGLHL-UHFFFAOYSA-N
PubChem Substance ID150634
InChIInChI=1S/C12H15NO/c1-2-12(9-8-11(14)13-12)10-6-4-3-5-7-10/h3-7H,2,8-9H2,1H3,(H,13,14)
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安全信息

RTECSUY5770700
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 25,790,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 25,790,1965

TYPE OF TEST            : LD54 - Lethal Dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 812 mg/kg
TOXIC EFFECTS :
   Behavioral - aggression
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,52,1966

系列性分类


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